PDB entry 4x21

View 4x21 on RCSB PDB site
Description: The MAP kinase JNK3 as target for halogen bonding
Class: transferase
Keywords: MAPK, halogen bond complex, transferase
Deposited on 2014-11-25, released 2015-11-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-12-02, with a file datestamp of 2015-11-27.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK10, JNK3, JNK3A, PRKM10, SAPK1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4x21a_
  • Chain 'B':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK10, JNK3, JNK3A, PRKM10, SAPK1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4x21b_
  • Heterogens: 3WH, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4x21A (A:)
ggsmskskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikkl
srpfqnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcq
viqmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartag
tsfmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkv
ieqlgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardl
lskmlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliy
kevmnse

    Sequence, based on observed residues (ATOM records): (download) 
    >4x21A (A:)
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglvtryyrapevilgmg
ykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyve
nrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyi
nvwydpaeveapppqiderehtieewkeliykevmn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4x21B (B:)
ggsmskskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikkl
srpfqnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcq
viqmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartag
tsfmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkv
ieqlgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardl
lskmlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliy
kevmnse

    Sequence, based on observed residues (ATOM records): (download) 
    >4x21B (B:)
qfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqthak
rayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldherm
syllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglavtryyrapevilgmg
ykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyve
nrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyi
nvwydpaeveapppqiderehtieewkeliykevmn