PDB entry 4rcp

View 4rcp on RCSB PDB site
Description: Crystal structure of Plk1 Polo-box domain in complex with PL-2
Class: Transferase/transferase inhibitor
Keywords: Polo-box domain, Transferase-transferase inhibitor complex
Deposited on 2014-09-16, released 2014-11-12
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-11-12, with a file datestamp of 2014-11-07.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.189
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK, PLK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4rcpa1, d4rcpa2
  • Chain 'B':
    Compound: pl-2
    Database cross-references and differences (RAF-indexed):
    • PDB 4RCP
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4rcpA (A:)
chlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdns
vgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehll
kaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavt
yidekrdfrtyrlslleeygcckelasrlryartmvdkllssrsasnr

    Sequence, based on observed residues (ATOM records): (download) 
    >4rcpA (A:)
chlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdns
vgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehll
kaganitpreglpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavtyidek
rdfrtyrlslleeygcckelasrlryartmvdkllssrsasnr

  • Chain 'B':
    No sequence available.