PDB entry 4qde

View 4qde on RCSB PDB site
Description: Dcps in complex with covalent inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: Decapping scavenger enzyme, residual cap structure cleavage, mRNA degradation, 3'->5' exosome-mediated mRNA decay pathway, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-05-13, released 2015-05-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-05-13, with a file datestamp of 2015-05-08.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: m7GpppX diphosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: DCPS, DCS1, HINT5, HSPC015
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qdea1, d4qdea2
  • Chain 'B':
    Compound: m7GpppX diphosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: DCPS, DCS1, HINT5, HSPC015
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qdeb1, d4qdeb2
  • Chain 'C':
    Compound: m7GpppX diphosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: DCPS, DCS1, HINT5, HSPC015
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qdec1, d4qdec2
  • Chain 'D':
    Compound: m7GpppX diphosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: DCPS, DCS1, HINT5, HSPC015
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qded1, d4qded2
  • Heterogens: PO4, 30S

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4qdeA (A:)
gadaapqlgkrkreldveeahaasteekeagvgngtcapvrlpfsgfrlqkvlresardk
iiflhgkvneasgdgdgedavvilektpfqveqvaqlltgspelqlqfsndiystyhlfp
prqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphlesqslsiqwvynil
dkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgirslrdltpehlpl
lrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfeapgsgverahllae
vienlecdprhyqqrtltfalraddpllkllqeaqqs

    Sequence, based on observed residues (ATOM records): (download) 
    >4qdeA (A:)
vrlpfsgfrlqkvlresardkiiflhgkvedavvilektpfqveqvaqlltgspelqlqf
sniystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphlesq
slsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgirs
lrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfeapg
sgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4qdeB (B:)
gadaapqlgkrkreldveeahaasteekeagvgngtcapvrlpfsgfrlqkvlresardk
iiflhgkvneasgdgdgedavvilektpfqveqvaqlltgspelqlqfsndiystyhlfp
prqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphlesqslsiqwvynil
dkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgirslrdltpehlpl
lrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfeapgsgverahllae
vienlecdprhyqqrtltfalraddpllkllqeaqqs

    Sequence, based on observed residues (ATOM records): (download) 
    >4qdeB (B:)
vrlpfsgfrlqkvlresardkiiflhgkvndavvilektpfqveqvaqlltgspelqlqf
sndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphles
qslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgir
slrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfeap
gsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4qdeC (C:)
gadaapqlgkrkreldveeahaasteekeagvgngtcapvrlpfsgfrlqkvlresardk
iiflhgkvneasgdgdgedavvilektpfqveqvaqlltgspelqlqfsndiystyhlfp
prqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphlesqslsiqwvynil
dkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgirslrdltpehlpl
lrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfeapgsgverahllae
vienlecdprhyqqrtltfalraddpllkllqeaqqs

    Sequence, based on observed residues (ATOM records): (download) 
    >4qdeC (C:)
pvrlpfsgfrlqkvlresardkiiflhgkgedavvilektpfqveqvaqlltgspelqlq
fsndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphle
sqslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgi
rslrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfea
pgsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4qdeD (D:)
gadaapqlgkrkreldveeahaasteekeagvgngtcapvrlpfsgfrlqkvlresardk
iiflhgkvneasgdgdgedavvilektpfqveqvaqlltgspelqlqfsndiystyhlfp
prqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphlesqslsiqwvynil
dkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgirslrdltpehlpl
lrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfeapgsgverahllae
vienlecdprhyqqrtltfalraddpllkllqeaqqs

    Sequence, based on observed residues (ATOM records): (download) 
    >4qdeD (D:)
apvrlpfsgfrlqkvlresardkiiflhgkvnegdgedavvilektpfqveqvaqllpel
qlqfsdiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlph
lesqslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrr
girslrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgf
eapgsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqqs