PDB entry 4pkl

View 4pkl on RCSB PDB site
Description: Bromodomain of Trypanosoma brucei BDF2 With IBET-151
Class: signaling protein/inhibitor
Keywords: SIGNALING PROTEIN, INHIBITOR, HISTONE, EPIGENETIC READER, SIGNALING PROTEIN-INHIBITOR complex
Deposited on 2014-05-15, released 2015-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-16, with a file datestamp of 2020-09-11.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain factor 2
    Species: Trypanosoma brucei brucei [TaxId:999953]
    Gene: Tb10.6k15.3240
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q38AM1 (4-End)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d4pkla1, d4pkla2
  • Chain 'B':
    Compound: Bromodomain factor 2
    Species: Trypanosoma brucei brucei [TaxId:999953]
    Gene: Tb10.6k15.3240
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pklb_
  • Heterogens: 1GH, PO4, K, CL, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pklA (A:)
gphmsfnkngclvfvsrlwdldklgmfhhpvsaeelpdyhtvikrpvdlssirdgiekgt
yatdvdvqndvarmitnaleynakgstwyqeamsfrktyldlarqsglvvdddeayips

    Sequence, based on observed residues (ATOM records): (download) 
    >4pklA (A:)
gphmsfnkngclvfvsrlwdldklgmfhhpvsaeelpdyhtvikrpvdlssirdgiekgt
yatdvdvqndvarmitnaleynakgstwyqeamsfrktyldlarqsglvv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4pklB (B:)
gphmsfnkngclvfvsrlwdldklgmfhhpvsaeelpdyhtvikrpvdlssirdgiekgt
yatdvdvqndvarmitnaleynakgstwyqeamsfrktyldlarqsglvvdddeayips

    Sequence, based on observed residues (ATOM records): (download) 
    >4pklB (B:)
sfnkngclvfvsrlwdldklgmfhhpvsaeelpdyhtvikrpvdlssirdgiekgtyatd
vdvqndvarmitnaleynakgstwyqeamsfrktyldlarqsglvvdd