PDB entry 4p24

View 4p24 on RCSB PDB site
Description: pore forming toxin
Class: toxin
Keywords: pore forming toxin
Deposited on 2014-03-01, released 2015-03-11
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-03-11, with a file datestamp of 2015-03-06.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:158878]
    Gene: SAV1163
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99UU6 (1-293)
      • engineered mutation (179)
      • engineered mutation (200)
    Domains in SCOPe 2.06: d4p24a_
  • Chain 'B':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:158878]
    Gene: SAV1163
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99UU6 (1-293)
      • engineered mutation (179)
      • engineered mutation (200)
    Domains in SCOPe 2.06: d4p24b_
  • Chain 'C':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:158878]
    Gene: SAV1163
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99UU6 (1-293)
      • engineered mutation (179)
      • engineered mutation (200)
    Domains in SCOPe 2.06: d4p24c_
  • Chain 'D':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:158878]
    Gene: SAV1163
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99UU6 (1-293)
      • engineered mutation (179)
      • engineered mutation (200)
    Domains in SCOPe 2.06: d4p24d_
  • Chain 'E':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:158878]
    Gene: SAV1163
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99UU6 (1-293)
      • engineered mutation (179)
      • engineered mutation (200)
    Domains in SCOPe 2.06: d4p24e_
  • Chain 'F':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:158878]
    Gene: SAV1163
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99UU6 (1-293)
      • engineered mutation (179)
      • engineered mutation (200)
    Domains in SCOPe 2.06: d4p24f_
  • Chain 'G':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:158878]
    Gene: SAV1163
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99UU6 (1-293)
      • engineered mutation (179)
      • engineered mutation (200)
    Domains in SCOPe 2.06: d4p24g_
  • Heterogens: MPD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4p24A (A:)
madsdiniktgttdigsnttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkg
tiagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltyg
fngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqna
gpydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkas
kqqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtnlehhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >4p24A (A:)
adsdiniktgttdigsttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkgti
agqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltygfn
gnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnagp
ydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkaskq
qtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4p24B (B:)
madsdiniktgttdigsnttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkg
tiagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltyg
fngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqna
gpydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkas
kqqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtnlehhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >4p24B (B:)
adsdiniktgttdigttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkgtia
gqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltygfng
nvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnagpy
drdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkaskqq
tnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4p24C (C:)
madsdiniktgttdigsnttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkg
tiagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltyg
fngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqna
gpydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkas
kqqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtnlehhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >4p24C (C:)
adsdiniktgttdigttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkgtia
gqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltygfng
nvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnagpy
drdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkaskqq
tnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4p24D (D:)
madsdiniktgttdigsnttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkg
tiagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltyg
fngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqna
gpydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkas
kqqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtnlehhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >4p24D (D:)
adsdiniktgttdignttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkgti
agqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltygfn
gnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnagp
ydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkaskq
qtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4p24E (E:)
madsdiniktgttdigsnttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkg
tiagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltyg
fngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqna
gpydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkas
kqqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtnlehhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >4p24E (E:)
adsdiniktgttdigttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkgtia
gqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltygfng
nvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnagpy
drdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkaskqq
tnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4p24F (F:)
madsdiniktgttdigsnttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkg
tiagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltyg
fngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqna
gpydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkas
kqqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtnlehhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >4p24F (F:)
adsdiniktgttdigtvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkgtiag
qyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltygfngn
vtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnagpyd
rdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkaskqqt
nidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4p24G (G:)
madsdiniktgttdigsnttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkg
tiagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltyg
fngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqna
gpydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkas
kqqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtnlehhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >4p24G (G:)
adsdiniktgttdigsttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkgti
agqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeymstltygfn
gnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnagp
ydrdswnpvygnqlfmktangsmkaaenfldpnkassllssgfspdfatvitmdrkaskq
qtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn