PDB entry 4jsp

View 4jsp on RCSB PDB site
Description: structure of mTORDeltaN-mLST8-ATPgammaS-Mg complex
Class: transferase
Keywords: Kinase, transferase
Deposited on 2013-03-22, released 2013-05-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-05-29, with a file datestamp of 2013-05-24.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.234
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase mTOR
    Species: Homo sapiens [TaxId:9606]
    Gene: FRAP, FRAP1, FRAP2, MTOR, RAFT1, RAPT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4jspa1, d4jspa2, d4jspa3
  • Chain 'B':
    Compound: Serine/threonine-protein kinase mTOR
    Species: Homo sapiens [TaxId:9606]
    Gene: FRAP, FRAP1, FRAP2, MTOR, RAFT1, RAPT1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Target of rapamycin complex subunit LST8
    Species: Homo sapiens [TaxId:9606]
    Gene: GBL, LST8, MLST8
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Target of rapamycin complex subunit LST8
    Species: Homo sapiens [TaxId:9606]
    Gene: GBL, LST8, MLST8
    Database cross-references and differences (RAF-indexed):
  • Heterogens: AGS, MG

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4jspA (A:)
    ddngivllgeraakcrayakalhykelefqkgptpaileslisinnklqqpeaaagvley
    amkhfgeleiqatwyeklhewedalvaydkkmdtnkddpelmlgrmrclealgewgqlhq
    qccekwtlvndetqakmarmaaaaawglgqwdsmeeytcmiprdthdgafyravlalhqd
    lfslaqqcidkardlldaeltamagesysraygamvschmlseleeviqyklvperreii
    rqiwwerlqgcqrivedwqkilmvrslvvsphedmrtwlkyaslcgksgrlalahktlvl
    llgvdpsrqldhplptvhpqvtyaymknmwksarkidafqhmqhfvqtmqqqaqhaiate
    dqqhkqelhklmarcflklgewqlnlqginestipkvlqyysaatehdrswykawhawav
    mnfeavlhykhqnqardekkklrhasganitnattaattaatatttastegsnseseaes
    tensptpsplqkkvtedlsktllmytvpavqgffrsislsrgnnlqdtlrvltlwfdygh
    wpdvnealvegvkaiqidtwlqvipqliaridtprplvgrlihqlltdigryhpqaliyp
    ltvaskstttarhnaankilknmcehsntlvqqammvseelirvailwhemwhegleeas
    rlyfgernvkgmfevleplhammergpqtlketsfnqaygrdlmeaqewcrkymksgnvk
    dltqawdlyyhvfrriskqlpqltslelqyvspkllmcrdlelavpgtydpnqpiiriqs
    iapslqvitskqrprkltlmgsnghefvfllkghedlrqdervmqlfglvntllandpts
    lrknlsiqryaviplstnsgligwvphcdtlhalirdyrekkkillniehrimlrmapdy
    dhltlmqkvevfehavnntagddlakllwlkspssevwfdrrtnytrslavmsmvgyilg
    lgdrhpsnlmldrlsgkilhidfgdcfevamtrekfpekipfrltrmltnamevtgldgn
    yritchtvmevlrehkdsvmavleafvydpllnwrlmdtntkgnkrsrtrtdsysagqsv
    eildgvelgepahkktgttvpesihsfigdglvkpealnkkaiqiinrvrdkltgrdfsh
    ddtldvptqvellikqatshenlcqcyigwcpfw
    

    Sequence, based on observed residues (ATOM records): (download)
    >4jspA (A:)
    eraakcrayakalhykelefqkgptpaileslisinnklqqpeaaagvleyamkhfgele
    iqatwyeklhewedalvaydkkmdtnkddpelmlgrmrclealgewgqlhqqccekwtlv
    ndetqakmarmaaaaawglgqwdsmeeytcmiprdthdgafyravlalhqdlfslaqqci
    dkardlldaeltamagesysraygamvschmlseleeviqyklvperreiirqiwwerlq
    gcqrivedwqkilmvrslvvsphedmrtwlkyaslcgksgrlalahktlvlllgvdpsrq
    ldhplptvhpqvtyaymknmwksarkidafqhmqhfvqtmqqqaqhaiatedqqhkqelh
    klmarcflklgewqlnlqginestipkvlqyysaatehdrswykawhawavmnfeavlhy
    khqnqardekkkvtedlsktllmytvpavqgffrsislsrgnnlqdtlrvltlwfdyghw
    pdvnealvegvkaiqidtwlqvipqliaridtprplvgrlihqlltdigryhpqaliypl
    tvaskstttarhnaankilknmcehsntlvqqammvseelirvailwhemwhegleeasr
    lyfgernvkgmfevleplhammergpqtlketsfnqaygrdlmeaqewcrkymksgnvkd
    ltqawdlyyhvfrriskqlpqltslelqyvspkllmcrdlelavpgtydpnqpiiriqsi
    apslqvitskqrprkltlmgsnghefvfllkghedlrqdervmqlfglvntllandptsl
    rknlsiqryaviplstnsgligwvphcdtlhalirdyrekkkillniehrimlrmapdyd
    hltlmqkvevfehavnntagddlakllwlkspssevwfdrrtnytrslavmsmvgyilgl
    gdrhpsnlmldrlsgkilhidfgdcfevamtrekfpekipfrltrmltnamevtgldgny
    ritchtvmevlrehkdsvmavleafvydpllnwrlmdtntalnkkaiqiinrvrdkltgr
    dfshddtldvptqvellikqatshenlcqcyigwcpfw
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.