SCOPe 2.07: Domain d4jspa3: 4jsp A:1385-2001

Lineage for d4jspa3 (4jsp A:1385-2001)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies)
   core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

4. Superfamily a.24.7: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1 family)
   automatically mapped to Pfam PF08771

5. Family a.24.7.1: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47213] (2 proteins)

6. Protein mTOR FKBP12–rapamycin-binding (FRB) domain [47214] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47215] (11 PDB entries)

8. Domain d4jspa3: 4jsp A:1385-2001 [345314]
   Other proteins in same PDB: d4jspa1
   complexed with ags, mg

Details for d4jspa3

PDB Entry: 4jsp, 3.3 Å

PDB Description: structure of mTORDeltaN-mLST8-ATPgammaS-Mg complex

PDB Compounds: (A:) Serine/threonine-protein kinase mTOR

SCOPe Domain Sequences for d4jspa3:

Sequence, based on SEQRES records:

>d4jspa3 a.24.7.1 (A:1385-2001) mTOR FKBP12–rapamycin-binding (FRB) domain {Human (Homo sapiens) [TaxId: 9606]}
eraakcrayakalhykelefqkgptpaileslisinnklqqpeaaagvleyamkhfgele
iqatwyeklhewedalvaydkkmdtnkddpelmlgrmrclealgewgqlhqqccekwtlv
ndetqakmarmaaaaawglgqwdsmeeytcmiprdthdgafyravlalhqdlfslaqqci
dkardlldaeltamagesysraygamvschmlseleeviqyklvperreiirqiwwerlq
gcqrivedwqkilmvrslvvsphedmrtwlkyaslcgksgrlalahktlvlllgvdpsrq
ldhplptvhpqvtyaymknmwksarkidafqhmqhfvqtmqqqaqhaiatedqqhkqelh
klmarcflklgewqlnlqginestipkvlqyysaatehdrswykawhawavmnfeavlhy
khqnqardekkklrhasganitnattaattaatatttastegsnseseaestensptpsp
lqkkvtedlsktllmytvpavqgffrsislsrgnnlqdtlrvltlwfdyghwpdvnealv
egvkaiqidtwlqvipqliaridtprplvgrlihqlltdigryhpqaliypltvaskstt
tarhnaankilknmceh

Sequence, based on observed residues (ATOM records):

>d4jspa3 a.24.7.1 (A:1385-2001) mTOR FKBP12–rapamycin-binding (FRB) domain {Human (Homo sapiens) [TaxId: 9606]}
eraakcrayakalhykelefqkgptpaileslisinnklqqpeaaagvleyamkhfgele
iqatwyeklhewedalvaydkkmdtnkddpelmlgrmrclealgewgqlhqqccekwtlv
ndetqakmarmaaaaawglgqwdsmeeytcmiprdthdgafyravlalhqdlfslaqqci
dkardlldaeltamagesysraygamvschmlseleeviqyklvperreiirqiwwerlq
gcqrivedwqkilmvrslvvsphedmrtwlkyaslcgksgrlalahktlvlllgvdpsrq
ldhplptvhpqvtyaymknmwksarkidafqhmqhfvqtmqqqaqhaiatedqqhkqelh
klmarcflklgewqlnlqginestipkvlqyysaatehdrswykawhawavmnfeavlhy
khqnqardekkkvtedlsktllmytvpavqgffrsislsrgnnlqdtlrvltlwfdyghw
pdvnealvegvkaiqidtwlqvipqliaridtprplvgrlihqlltdigryhpqaliypl
tvaskstttarhnaankilknmceh

Timeline for d4jspa3:

• d4jspa3 is new in SCOPe 2.07-stable
  
• d4jspa3 appears in the current release, SCOPe 2.08