PDB entry 4j0o

View 4j0o on RCSB PDB site
Description: Structure of the Y246A Mutant of the PANTON-VALENTINE LEUCOCIDIN S Component from STAPHYLOCOCCUS AUREUS
Class: toxin
Keywords: BI-COMPONENT LEUCOTOXIN, STAPHYLOCOCCUS AUREUS, S COMPONENT LEUCOCIDIN, beta-barrel pore forming toxin, TOXIN
Deposited on 2013-01-31, released 2014-01-29
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-04-23, with a file datestamp of 2014-04-18.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.185
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: LukS-PV
    Species: Staphylococcus phage PVL [TaxId:71366]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O80066 (Start-290)
      • engineered mutation (252)
    Domains in SCOPe 2.06: d4j0oa_
  • Chain 'B':
    Compound: LukS-PV
    Species: Staphylococcus phage PVL [TaxId:71366]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O80066 (Start-290)
      • engineered mutation (252)
    Domains in SCOPe 2.06: d4j0ob_
  • Chain 'C':
    Compound: LukS-PV
    Species: Staphylococcus phage PVL [TaxId:71366]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4j0oc_
  • Chain 'D':
    Compound: LukS-PV
    Species: Staphylococcus phage PVL [TaxId:71366]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O80066 (Start-290)
      • engineered mutation (252)
    Domains in SCOPe 2.06: d4j0od_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4j0oA (A:)
gplgspefnnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgf
inskttyynykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyni
ggnfnsgpstggngsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsgh
dpnlfvgykpysqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrn
mdvthatrrtthagnsylegsrihnafvnrnytvkyevnwktheikvkghn

    Sequence, based on observed residues (ATOM records): (download) 
    >4j0oA (A:)
nienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgfinskttyyn
ykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyniggnfnsgng
sfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsghdpnlfvgykpysqn
prdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrnmdvthatrrtagns
ylegsrihnafvnrnytvkyevnwktheikvkghn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4j0oB (B:)
gplgspefnnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgf
inskttyynykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyni
ggnfnsgpstggngsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsgh
dpnlfvgykpysqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrn
mdvthatrrtthagnsylegsrihnafvnrnytvkyevnwktheikvkghn

    Sequence, based on observed residues (ATOM records): (download) 
    >4j0oB (B:)
nienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgfinskttyyn
ykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyniggnfnsgps
tgsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsghdpnlfvgykpys
qnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrnmdvthatrrtag
nsylegsrihnafvnrnytvkyevnwktheikvkghn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4j0oC (C:)
gplgspefnnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgf
inskttyynykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyni
ggnfnsgpstggngsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsgh
dpnlfvgykpysqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrn
mdvthatrrtthagnsylegsrihnafvnrnytvkyevnwktheikvkghn

    Sequence, based on observed residues (ATOM records): (download) 
    >4j0oC (C:)
nienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgfinskttyyn
ykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyniggnfnsgps
sfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsghdpnlfvgykpysqn
prdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrnmdvthatrrttgns
ylegsrihnafvnrnytvkyevnwktheikvkghn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4j0oD (D:)
gplgspefnnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgf
inskttyynykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyni
ggnfnsgpstggngsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsgh
dpnlfvgykpysqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrn
mdvthatrrtthagnsylegsrihnafvnrnytvkyevnwktheikvkghn

    Sequence, based on observed residues (ATOM records): (download) 
    >4j0oD (D:)
nienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgfinskttyyn
ykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyniggnfnsgfn
ysktisynqqnyisevehqnsksvqwgikansfitslgkmsghdpnlfvgykpysqnprd
yfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrnmdvthatrrtagnsyle
gsrihnafvnrnytvkyevnwktheikvkghn