PDB entry 4b3u

View 4b3u on RCSB PDB site
Description: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
Class: transferase
Keywords: transferase, thymidylyltransferase, allosteric inhibitor
Deposited on 2012-07-26, released 2012-10-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-03-06, with a file datestamp of 2013-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.22
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (10-302)
      • expression tag (0-5)
    Domains in SCOPe 2.07: d4b3ua1, d4b3ua2
  • Chain 'B':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4b3ub_
  • Chain 'C':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (10-302)
      • expression tag (1-5)
    Domains in SCOPe 2.07: d4b3uc1, d4b3uc2
  • Chain 'D':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4b3ud_
  • Heterogens: NWL, CL, GOL, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4b3uA (A:)
hhhhhhgsmamkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagire
iliistpqdtprfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgd
nlyyghdfhellgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksny
avtglyfydqqvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthd
slleagqfiatlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrllte
tvy

    Sequence, based on observed residues (ATOM records): (download) 
    >4b3uA (A:)
hhhhhhmkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireilii
stpqdtprfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyy
ghdfhellgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtg
lyfydqqvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslle
agqfiatlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4b3uB (B:)
hhhhhhgsmamkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagire
iliistpqdtprfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgd
nlyyghdfhellgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksny
avtglyfydqqvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthd
slleagqfiatlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrllte
tvy

    Sequence, based on observed residues (ATOM records): (download) 
    >4b3uB (B:)
mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4b3uC (C:)
hhhhhhgsmamkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagire
iliistpqdtprfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgd
nlyyghdfhellgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksny
avtglyfydqqvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthd
slleagqfiatlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrllte
tvy

    Sequence, based on observed residues (ATOM records): (download) 
    >4b3uC (C:)
hhhhhmkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliis
tpqdtprfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyg
hdfhellgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtgl
yfydqqvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdsllea
gqfiatlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4b3uD (D:)
hhhhhhgsmamkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagire
iliistpqdtprfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgd
nlyyghdfhellgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksny
avtglyfydqqvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthd
slleagqfiatlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrllte
tvy

    Sequence, based on observed residues (ATOM records): (download) 
    >4b3uD (D:)
mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy