PDB entry 4b1i

View 4b1i on RCSB PDB site
Description: Structure of human PARG catalytic domain in complex with OA-ADP-HPD
Class: hydrolase
Keywords: poly ADP-ribose, hydrolase
Deposited on 2012-07-10, released 2012-12-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-01-16, with a file datestamp of 2013-01-11.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: 0.16235
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly(ADP-ribose) glycohydrolase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86W56
      • engineered mutation (170-172)
      • engineered mutation (242-244)
    Domains in SCOPe 2.06: d4b1ia_
  • Heterogens: DTV, GOL, A8P, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4b1iA (A:)
gsspdkkwlgtpieemrrmprcgirlpllrpsanhtvtirvdllragevpkpfpthykdl
wdnkhvkmpcseqnlypvedengertagsrweliqtallnkftrpqnlkdailkynvays
kkwdftalidfwdkvleeaeaqhlyqsilpdmvkialclpnictqpipllaaamnhsitm
sqeqiasllanaffctfprrnakmkseyssypdinfnrlfegrssrkpeklktlfcyfrr
vtaaaptglvtftrqsledfpewercekpltrlhvtyegtieengqgmlqvdfanrfvgg
gvtsaglvqeeirflinpeliisrlftevldhnecliitgteqyseytgyaetyrwsrsh
edgserddwqrrcteivaidalhfrryldqfvpekmrrelnkaycgflrpgvssenlsav
atgnwgcgafggdarlkaliqilaaaaaerdvvyftfgdselmrdiysmhiflterkltv
gdvyklllryyneecrncstpgpdiklypfiyhavescaetadhsgqrtgt

    Sequence, based on observed residues (ATOM records): (download) 
    >4b1iA (A:)
dkkwlgtpieemrrmprcgirlpllrpsanhtvtirvdllragevpkpfpthykdlwdnk
hvkmpcseqnlypvtagsrweliqtallnkftrpqnlkdailkynvayskkwdftalidf
wdkvleeaeaqhlyqsilpdmvkialclpnictqpipllaaamnhsitmsqeqiasllan
affctfprrnakmkseyssypdinfnrlfegrssrkpeklktlfcyfrrvtaaaptglvt
ftrqsledfpewercekpltrlhvtyegtieengqgmlqvdfanrfvgggvtsaglvqee
irflinpeliisrlftevldhnecliitgteqyseytgyaetyrwsrshedgserddwqr
rcteivaidalhfrryldqfvpekmrrelnkaycgflrpgvssenlsavatgnwgcgafg
gdarlkaliqilaaaaaerdvvyftfgdselmrdiysmhiflterkltvgdvyklllryy
neecrncstpgpdiklypfiyhavesc