PDB entry 3t7c

View 3t7c on RCSB PDB site
Description: Crystal structure of carveol dehydrogenase from Mycobacterium avium bound to NAD
Class: oxidoreductase
Keywords: Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, SSGCID, MAV_1393, (+)-trans-carveol dehydrogenase, nicotinamide adenine dinucleotide, NAD, (+)-(S)-carvone, ortholog, OXIDOREDUCTASE
Deposited on 2011-07-29, released 2011-08-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-02-08, with a file datestamp of 2017-02-03.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: carveol dehydrogenase
    Species: Mycobacterium avium [TaxId:243243]
    Gene: MAV_1393
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0QCJ8 (21-298)
      • engineered mutation (250)
    Domains in SCOPe 2.07: d3t7ca_
  • Chain 'B':
    Compound: carveol dehydrogenase
    Species: Mycobacterium avium [TaxId:243243]
    Gene: MAV_1393
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0QCJ8 (Start-298)
      • engineered mutation (250)
    Domains in SCOPe 2.07: d3t7cb_
  • Chain 'C':
    Compound: carveol dehydrogenase
    Species: Mycobacterium avium [TaxId:243243]
    Gene: MAV_1393
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0QCJ8 (21-298)
      • engineered mutation (250)
    Domains in SCOPe 2.07: d3t7cc_
  • Chain 'D':
    Compound: carveol dehydrogenase
    Species: Mycobacterium avium [TaxId:243243]
    Gene: MAV_1393
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0QCJ8 (Start-298)
      • engineered mutation (250)
    Domains in SCOPe 2.07: d3t7cd_
  • Heterogens: NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3t7cA (A:)
mahhhhhhmgtleaqtqgpgsmagkvegkvafitgaargqgrshaitlaregadiiaidv
ckqldgvklpmstpddlaetvrqvealgrriiasqvdvrdfdamqaavddgvtqlgrldi
vlanaalasegtrlnrmdpktwrdmidvnlngawitarvaiphimagkrggsivftssig
glrgaenignyiaskhglhglmrtmalelgprnirvnivcpssvatpmllneptyrmfrp
dlenptvedfqvasrqmhvlpipyvepadisnailflvsddaryitgvslpvdggallk

    Sequence, based on observed residues (ATOM records): (download) 
    >3t7cA (A:)
magkvegkvafitgaargqgrshaitlaregadiiaidvckqldgvklpmstpddlaetv
rqvealgrriiasqvdvrdfdamqaavddgvtqlgrldivlanaalasegtrlnrmdpkt
wrdmidvnlngawitarvaiphimagkrggsivftssigglrgaenignyiaskhglhgl
mrtmalelgprnirvnivcpssvatpmllneptyrmfrpdlenptvedfqvasrqmhvlp
ipyvepadisnailflvsddaryitgvslpvdggallk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3t7cB (B:)
mahhhhhhmgtleaqtqgpgsmagkvegkvafitgaargqgrshaitlaregadiiaidv
ckqldgvklpmstpddlaetvrqvealgrriiasqvdvrdfdamqaavddgvtqlgrldi
vlanaalasegtrlnrmdpktwrdmidvnlngawitarvaiphimagkrggsivftssig
glrgaenignyiaskhglhglmrtmalelgprnirvnivcpssvatpmllneptyrmfrp
dlenptvedfqvasrqmhvlpipyvepadisnailflvsddaryitgvslpvdggallk

    Sequence, based on observed residues (ATOM records): (download) 
    >3t7cB (B:)
agkvegkvafitgaargqgrshaitlaregadiiaidvckqldgvklpmstpddlaetvr
qvealgrriiasqvdvrdfdamqaavddgvtqlgrldivlanaalasegtrlnrmdpktw
rdmidvnlngawitarvaiphimagkrggsivftssigglrgaenignyiaskhglhglm
rtmalelgprnirvnivcpssvatpmllneptyrmfrpdlenptvedfqvasrqmhvlpi
pyvepadisnailflvsddaryitgvslpvdggallk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3t7cC (C:)
mahhhhhhmgtleaqtqgpgsmagkvegkvafitgaargqgrshaitlaregadiiaidv
ckqldgvklpmstpddlaetvrqvealgrriiasqvdvrdfdamqaavddgvtqlgrldi
vlanaalasegtrlnrmdpktwrdmidvnlngawitarvaiphimagkrggsivftssig
glrgaenignyiaskhglhglmrtmalelgprnirvnivcpssvatpmllneptyrmfrp
dlenptvedfqvasrqmhvlpipyvepadisnailflvsddaryitgvslpvdggallk

    Sequence, based on observed residues (ATOM records): (download) 
    >3t7cC (C:)
magkvegkvafitgaargqgrshaitlaregadiiaidvckqldgvklpmstpddlaetv
rqvealgrriiasqvdvrdfdamqaavddgvtqlgrldivlanaalasegtrlnrmdpkt
wrdmidvnlngawitarvaiphimagkrggsivftssigglrgaenignyiaskhglhgl
mrtmalelgprnirvnivcpssvatpmllneptyrmfrpdlenptvedfqvasrqmhvlp
ipyvepadisnailflvsddaryitgvslpvdggallk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3t7cD (D:)
mahhhhhhmgtleaqtqgpgsmagkvegkvafitgaargqgrshaitlaregadiiaidv
ckqldgvklpmstpddlaetvrqvealgrriiasqvdvrdfdamqaavddgvtqlgrldi
vlanaalasegtrlnrmdpktwrdmidvnlngawitarvaiphimagkrggsivftssig
glrgaenignyiaskhglhglmrtmalelgprnirvnivcpssvatpmllneptyrmfrp
dlenptvedfqvasrqmhvlpipyvepadisnailflvsddaryitgvslpvdggallk

    Sequence, based on observed residues (ATOM records): (download) 
    >3t7cD (D:)
agkvegkvafitgaargqgrshaitlaregadiiaidvckqldgvklpmstpddlaetvr
qvealgrriiasqvdvrdfdamqaavddgvtqlgrldivlanaalasegtrlnrmdpktw
rdmidvnlngawitarvaiphimagkrggsivftssigglrgaenignyiaskhglhglm
rtmalelgprnirvnivcpssvatpmllneptyrmfrptvedfqvasrqmhvlpipyvep
adisnailflvsddaryitgvslpvdggallk