PDB entry 3t60

View 3t60 on RCSB PDB site
Description: 5'-Diphenyl Nucleoside Inhibitors of Plasmodium falciparum dUTPase
Class: hydrolase/hydrolase inhibitor
Keywords: Trimeric dUTPase, dUTP binding, Nucleus, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-07-28, released 2012-08-29
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-08-29, with a file datestamp of 2012-08-24.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.199
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: PF11_0282
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3t60a_
  • Chain 'B':
    Compound: Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: PF11_0282
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3t60b_
  • Chain 'C':
    Compound: Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: PF11_0282
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3t60c_
  • Heterogens: DUA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3t60A (A:)
mhlkivclsdevremyknhkthhegdsgldlfivkdevlkpksttfvklgikaialqyks
nyyykceksenkkkdddksnivntsfllfprssisktplrlansiglidagyrgeiiaal
dntsdqeyhikkndklvqlvsftgeplsfelveeldetsrgeggfgstsnnkylehhhhh
h

    Sequence, based on observed residues (ATOM records): (download) 
    >3t60A (A:)
mhlkivclsdevremykndsgldlfivkdevlkpksttfvklgikaialqyksnyynivn
tsfllfprssisktplrlansiglidagyrgeiiaaldntsdqeyhikkndklvqlvsft
geplsfelveeldetsrgeggfg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3t60B (B:)
mhlkivclsdevremyknhkthhegdsgldlfivkdevlkpksttfvklgikaialqyks
nyyykceksenkkkdddksnivntsfllfprssisktplrlansiglidagyrgeiiaal
dntsdqeyhikkndklvqlvsftgeplsfelveeldetsrgeggfgstsnnkylehhhhh
h

    Sequence, based on observed residues (ATOM records): (download) 
    >3t60B (B:)
mhlkivclsdevremykndsgldlfivkdevlkpksttfvklgikaialqyksnyyykni
vntsfllfprssisktplrlansiglidagyrgeiiaaldntsdqeyhikkndklvqlvs
ftgeplsfelv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3t60C (C:)
mhlkivclsdevremyknhkthhegdsgldlfivkdevlkpksttfvklgikaialqyks
nyyykceksenkkkdddksnivntsfllfprssisktplrlansiglidagyrgeiiaal
dntsdqeyhikkndklvqlvsftgeplsfelveeldetsrgeggfgstsnnkylehhhhh
h

    Sequence, based on observed residues (ATOM records): (download) 
    >3t60C (C:)
mhlkivclsdevremykndsgldlfivkdevlkpksttfvklgikaialqyksnyyykni
vntsfllfprssisktplrlansiglidagyrgeiiaaldntsdqeyhikkndklvqlvs
ftgeplsfelveeldetsrgeggfg