PDB entry 3rhu
View 3rhu on RCSB PDB site
Description: Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins
Class: de novo protein
Keywords: protein grafting, flexible backbone design, epitope-scaffold, HIV, immunogen design, DE NOVO PROTEIN
Deposited on
2011-04-12, released
2011-11-09
The last revision prior to the SCOPe 2.06 freeze date was dated
2012-01-18, with a file datestamp of
2012-01-13.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.282
AEROSPACI score: 0.17
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: SC_1wnu
Species: Pyrococcus horikoshii [TaxId:70601]
Gene: alaXS, PH0574
Database cross-references and differences (RAF-indexed):
- Uniprot O58307 (Start-44)
- engineered mutation (21-22)
- engineered mutation (25)
- engineered mutation (30)
- Uniprot O58307 (60-End)
Domains in SCOPe 2.06: d3rhua_ - Chain 'B':
Compound: SC_1wnu
Species: Pyrococcus horikoshii [TaxId:70601]
Gene: alaXS, PH0574
Database cross-references and differences (RAF-indexed):
- Uniprot O58307 (Start-44)
- engineered mutation (21-22)
- engineered mutation (25)
- engineered mutation (30)
- Uniprot O58307 (60-End)
Domains in SCOPe 2.06: d3rhub_
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3rhuA (A:)
sysievrthsalhvvkgavvktagsdakwttstyvkgnkgvlivkaalepdkwgiaaiea
lanekvkenapikiyelpreeaekmfgedmydlfpvpedvrilkvvviedwnvnacnkeh
tkttgeigpikirkvrfrkskglleihfellelehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3rhuA (A:)
ysievrthsalhvvkgavvktagsdakwttstyvkgnkgvlivkaalepdkwgiaaieal
anekvkenapikiyelpreeaekmfgedmydilkvvviedwnvnacnkehtkttgeigpi
kirkvrfrkskglleihfell
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3rhuB (B:)
sysievrthsalhvvkgavvktagsdakwttstyvkgnkgvlivkaalepdkwgiaaiea
lanekvkenapikiyelpreeaekmfgedmydlfpvpedvrilkvvviedwnvnacnkeh
tkttgeigpikirkvrfrkskglleihfellelehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3rhuB (B:)
ysievrthsalhvvkgavvktagsdakwttstyvkgnkgvlivkaalepdkwgiaaieal
anekvkenapikiyelpreeaekmfgedmydilkvvviedwnvnacnkehtkttgeigpi
kirkvrfrkskglleihfell