PDB entry 3rf3

View 3rf3 on RCSB PDB site
Description: Shigella IpaA-VBS3 in complex with human vinculin
Class: protein binding/toxin
Keywords: alpha-helix bundle domain, cytoskeletal protein, protein-protein interactions, cell adhesion, cytoskeleton, bacterial toxins, pathogen-host interactions, IpaA, Talin, F-actin, phosphatidylinositol 4 5-bisphosphate, Cytosol, Focal adhesion, protein binding-toxin complex
Deposited on 2011-04-05, released 2011-04-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-05-23, with a file datestamp of 2012-05-18.
Experiment type: XRAY
Resolution: 1.61 Å
R-factor: 0.184
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: vinculin
    Species: Homo sapiens [TaxId:9606]
    Gene: VCL, vinculin
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3rf3a1
  • Chain 'B':
    Compound: vinculin
    Species: Homo sapiens [TaxId:9606]
    Gene: VCL, vinculin
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3rf3b1, d3rf3b2
  • Chain 'C':
    Compound: Invasin ipaA
    Species: Shigella flexneri [TaxId:623]
    Gene: CP0125, ipaA
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Invasin ipaA
    Species: Shigella flexneri [TaxId:623]
    Gene: CP0125, ipaA
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CAC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rf3A (A:)
mpvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnlvrvgke
tvqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgilsgts
dllltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderqq
elthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvekmsae
ineiirvlqltswdedaw

    Sequence, based on observed residues (ATOM records): (download) 
    >3rf3A (A:)
pvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnlvrvgket
vqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgilsgtsd
llltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderqqe
lthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvekmsaei
neiirvlqltswdedaw

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3rf3B (B:)
mpvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnlvrvgke
tvqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgilsgts
dllltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderqq
elthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvekmsae
ineiirvlqltswdedaw

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.