PDB entry 3qtl

View 3qtl on RCSB PDB site
Description: Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin
Class: hydrolase/hydrolase inhibitor
Keywords: SERINE PROTEASE -KAZAL TYPE SERINE PROTEASE INHIBITOR COMPLEX, HYDROLASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-02-23, released 2011-06-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-06-01, with a file datestamp of 2011-05-27.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.204
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Subtilisin-like serin protease
    Species: Bacillus licheniformis [TaxId:1402]
    Gene: aprE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qtla_
  • Chain 'B':
    Compound: Subtilisin-like serin protease
    Species: Bacillus licheniformis [TaxId:1402]
    Gene: aprE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qtlb_
  • Chain 'C':
    Compound: Subtilisin-like serin protease
    Species: Bacillus licheniformis [TaxId:1402]
    Gene: aprE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3qtlc_
  • Chain 'D':
    Compound: Kazal-type serine protease inhibitor SPI-1
    Species: Carcinoscorpius rotundicauda [TaxId:6848]
    Gene: SPI-1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qtlA (A:)
aqtvpygiplikadkvqaqgfkganvkvavldtgiqashpdlnvvggasfvageayntdg
nghgthvagtvaaldnttgvlgvapsvslyavkvlnssgsgsysgivsgiewattngmdv
inmslggasgstamkqavdnayargvvvvaaagnsgssgntntigypakydsviavgavd
snsnrasfssvgaelevmapgagvystyptntyatlngtsmasphvagaaalilskhpnl
sasqvrnrlsstatylgssfyygkglinveaaaq

    Sequence, based on observed residues (ATOM records): (download) 
    >3qtlA (A:)
aqtvpygiplikadkvqaqgfkganvkvavldtgiqashpdlnvvggasfvageayntdg
nghgthvagtvaaldnttgvlgvapsvslyavkvlnssgsgsysgivsgiewattngmdv
inmslggasgstamkqavdnayargvvvvaaagnsgntigypakydsviavgavdsnsnr
asfssvgaelevmapgagvystyptntyatlngtsmasphvagaaalilskhpnlsasqv
rnrlsstatylgssfyygkglinveaaaq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3qtlB (B:)
aqtvpygiplikadkvqaqgfkganvkvavldtgiqashpdlnvvggasfvageayntdg
nghgthvagtvaaldnttgvlgvapsvslyavkvlnssgsgsysgivsgiewattngmdv
inmslggasgstamkqavdnayargvvvvaaagnsgssgntntigypakydsviavgavd
snsnrasfssvgaelevmapgagvystyptntyatlngtsmasphvagaaalilskhpnl
sasqvrnrlsstatylgssfyygkglinveaaaq

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3qtlC (C:)
aqtvpygiplikadkvqaqgfkganvkvavldtgiqashpdlnvvggasfvageayntdg
nghgthvagtvaaldnttgvlgvapsvslyavkvlnssgsgsysgivsgiewattngmdv
inmslggasgstamkqavdnayargvvvvaaagnsgssgntntigypakydsviavgavd
snsnrasfssvgaelevmapgagvystyptntyatlngtsmasphvagaaalilskhpnl
sasqvrnrlsstatylgssfyygkglinveaaaq

  • Chain 'D':
    No sequence available.