PDB entry 3qpz

View 3qpz on RCSB PDB site
Description: Crystal structure of the N59A mutant of the 3-deoxy-d-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis
Class: transferase
Keywords: MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8P, KDOPS, KDO8PS, Tim Barrel, Transferase
Deposited on 2011-02-14, released 2011-04-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-03-05, with a file datestamp of 2014-02-28.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.182
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
    Species: Neisseria meningitidis [TaxId:122586]
    Gene: kdsA, NMB1283
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZ55 (0-End)
      • engineered mutation (58)
    Domains in SCOPe 2.07: d3qpza_
  • Chain 'B':
    Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
    Species: Neisseria meningitidis [TaxId:122586]
    Gene: kdsA, NMB1283
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZ55 (0-End)
      • engineered mutation (58)
    Domains in SCOPe 2.07: d3qpzb_
  • Chain 'C':
    Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
    Species: Neisseria meningitidis [TaxId:122586]
    Gene: kdsA, NMB1283
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZ55 (0-End)
      • engineered mutation (58)
    Domains in SCOPe 2.07: d3qpzc_
  • Chain 'D':
    Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
    Species: Neisseria meningitidis [TaxId:122586]
    Gene: kdsA, NMB1283
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZ55 (0-End)
      • engineered mutation (58)
    Domains in SCOPe 2.07: d3qpzd_
  • Heterogens: CL, PO4, GOL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qpzA (A:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdkaar
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtrdagsaasggrraqaldlalagmatrlaglfleshpd
pklakcdgpsalplhlledflirikalddliksqpiltie

    Sequence, based on observed residues (ATOM records): (download) 
    >3qpzA (A:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdkaar
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqgrraqaldlalagmatrlaglflesplhlledflirik
alddliksqpi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qpzB (B:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdkaar
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtrdagsaasggrraqaldlalagmatrlaglfleshpd
pklakcdgpsalplhlledflirikalddliksqpiltie

    Sequence, based on observed residues (ATOM records): (download) 
    >3qpzB (B:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdkaar
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqgrraqaldlalagmatrlaglfleshlledflirikal
ddliksqpilti

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3qpzC (C:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdkaar
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtrdagsaasggrraqaldlalagmatrlaglfleshpd
pklakcdgpsalplhlledflirikalddliksqpiltie

    Sequence, based on observed residues (ATOM records): (download) 
    >3qpzC (C:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdkaar
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslraqaldlalagmatrlaglfleshalplhlledflirik
alddliksqpil

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3qpzD (D:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdkaar
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtrdagsaasggrraqaldlalagmatrlaglfleshpd
pklakcdgpsalplhlledflirikalddliksqpiltie

    Sequence, based on observed residues (ATOM records): (download) 
    >3qpzD (D:)
mdikinditlgnnspfvlfgginvlesldstlqtcahyvevtrklgipyifkasfdkaar
ssihsyrgvgleeglkifekvkaefgipvitdvhephqcqpvaevcdviqlpaflarqtd
lvvamaktgnvvnikkpqflspsqmknivekfheagngklilcergssfgydnlvvdmlg
fgvmkqtcgnlpvifdvthslqtaqaldlalagmatrlaglfleshsalplhlledflir
ikalddliksqpil