PDB entry 3q2p

View 3q2p on RCSB PDB site
Description: Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix
Class: plant protein
Keywords: sweet protein, sweet receptor, T1R2:T1R3, PLANT PROTEIN
Deposited on 2010-12-20, released 2011-04-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-08-02, with a file datestamp of 2017-07-28.
Experiment type: XRAY
Resolution: 2.34 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Monellin chain B/Monellin chain A chimeric protein
    Species: Dioscoreophyllum cumminsii [TaxId:3457]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02882 (1-50)
      • engineered mutation (16)
      • engineered mutation (37)
      • conflict (49-50)
      • linker (51-52)
    • Uniprot P02881 (53-96)
    Domains in SCOPe 2.07: d3q2pa_
  • Chain 'B':
    Compound: Monellin chain B/Monellin chain A chimeric protein
    Species: Dioscoreophyllum cumminsii [TaxId:3457]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02882 (1-50)
      • initiating methionine (0)
      • engineered mutation (16)
      • engineered mutation (37)
      • conflict (49-50)
      • linker (51-52)
    • Uniprot P02881 (53-96)
    Domains in SCOPe 2.07: d3q2pb_
  • Chain 'C':
    Compound: Monellin chain B/Monellin chain A chimeric protein
    Species: Dioscoreophyllum cumminsii [TaxId:3457]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02882 (1-50)
      • engineered mutation (16)
      • engineered mutation (37)
      • conflict (49-50)
      • linker (51-52)
    • Uniprot P02881 (53-96)
    Domains in SCOPe 2.07: d3q2pc_
  • Chain 'D':
    Compound: Monellin chain B/Monellin chain A chimeric protein
    Species: Dioscoreophyllum cumminsii [TaxId:3457]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02882 (1-50)
      • engineered mutation (16)
      • engineered mutation (37)
      • conflict (49-50)
      • linker (51-52)
    • Uniprot P02881 (53-96)
    Domains in SCOPe 2.07: d3q2pd_
  • Heterogens: NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3q2pA (A:)
mgeweiidigpftqnlakfavdeenkigqygrltfnkairpcmkktiyenegfreikgye
yqlyvyasdklfradisedyktrgrkllrfngpvppp

    Sequence, based on observed residues (ATOM records): (download) 
    >3q2pA (A:)
geweiidigpftqnlakfavdeenkigqygrltfnkairpcmkktiyenegfreikgyey
qlyvyasdklfradisedyktrgrkllrfngpvppp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3q2pB (B:)
mgeweiidigpftqnlakfavdeenkigqygrltfnkairpcmkktiyenegfreikgye
yqlyvyasdklfradisedyktrgrkllrfngpvppp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3q2pC (C:)
mgeweiidigpftqnlakfavdeenkigqygrltfnkairpcmkktiyenegfreikgye
yqlyvyasdklfradisedyktrgrkllrfngpvppp

    Sequence, based on observed residues (ATOM records): (download) 
    >3q2pC (C:)
geweiidigpftqnlakfavdeenkigqygrltfnkairpcmkktiyenegfreikgyey
qlyvyasdklfradisedyktrgrkllrfngpvppp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3q2pD (D:)
mgeweiidigpftqnlakfavdeenkigqygrltfnkairpcmkktiyenegfreikgye
yqlyvyasdklfradisedyktrgrkllrfngpvppp

    Sequence, based on observed residues (ATOM records): (download) 
    >3q2pD (D:)
geweiidigpftqnlakfavdeenkigqygrltfnkairpcmkktiyenegfreikgyey
qlyvyasdklfradisedyktrgrkllrfngpvppp