PDB entry 3oth

View 3oth on RCSB PDB site
Description: Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP and calicheamicin alpha3I bound form
Class: transferase/antibiotic
Keywords: Calicheamicin, TDP, Structural Genomics, PSI-2, Protein Structure Initiative, Center for Eukaryotic Structural Genomics, CESG, GT-B fold, Glycosyltransferase, transferase-antibiotic complex, Enzyme Discovery for Natural Product Biosynthesis, NatPro
Deposited on 2010-09-11, released 2010-12-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: CalG1
    Species: Micromonospora echinospora [TaxId:1877]
    Gene: calG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8KNF2 (20-End)
      • expression tag (13-19)
    Domains in SCOPe 2.08: d3otha1, d3otha2
  • Chain 'B':
    Compound: CalG1
    Species: Micromonospora echinospora [TaxId:1877]
    Gene: calG1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3othb_
  • Heterogens: TYD, CLJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3othA (A:)
ghhhhhhhhhhssghiegrhmrvlfaslgthghtypllplataaraaghevtfatgegfa
gtlrklgfepvatgmpvfdgflaalrirfdtdspegltpeqlselpqivfgrvipqrvfd
elqpvierlrpdlvvqeisnygaglaalkagiptichgvgrdtpddltrsieeevrglaq
rlgldlppgridgfgnpfidifppslqepefrarprrhelrpvpfaeqgdlpawlssrdt
arplvyltlgtssggtvevlraaidglagldadvlvasgpsldvsglgevpanvrleswv
pqaallphvdlvvhhggsgttlgalgagvpqlsfpwagdsfanaqavaqagagdhllpdn
ispdsvsgaakrllaeesyragaravaaeiaampgpdevvrllpgfasrsag

    Sequence, based on observed residues (ATOM records): (download) 
    >3othA (A:)
ghiegrhmrvlfaslgthghtypllplataaraaghevtfatgegfagtlrklgfepvat
gmpvfdgflaalrirfdtdspegltpeqlselpqivfgrvipqrvfdelqpvierlrpdl
vvqeisnygaglaalkagiptichgvgrdtpddltrsieeevrglaqrlgldlppgridg
fgnpfidifppslqepefrarprrhelrpvpfaeqgdlpawlssrdtarplvyltlgtss
ggtvevlraaidglagldadvlvasgpsldvsglgevpanvrleswvpqaallphvdlvv
hhggsgttlgalgagvpqlsfpwagdsfanaqavaqagagdhllpdnispdsvsgaakrl
laeesyragaravaaeiaampgpdevvrllpgfas

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3othB (B:)
ghhhhhhhhhhssghiegrhmrvlfaslgthghtypllplataaraaghevtfatgegfa
gtlrklgfepvatgmpvfdgflaalrirfdtdspegltpeqlselpqivfgrvipqrvfd
elqpvierlrpdlvvqeisnygaglaalkagiptichgvgrdtpddltrsieeevrglaq
rlgldlppgridgfgnpfidifppslqepefrarprrhelrpvpfaeqgdlpawlssrdt
arplvyltlgtssggtvevlraaidglagldadvlvasgpsldvsglgevpanvrleswv
pqaallphvdlvvhhggsgttlgalgagvpqlsfpwagdsfanaqavaqagagdhllpdn
ispdsvsgaakrllaeesyragaravaaeiaampgpdevvrllpgfasrsag

    Sequence, based on observed residues (ATOM records): (download) 
    >3othB (B:)
mrvlfaslgthghtypllplataaraaghevtfatgegfagtlrklgfepvatgmpvfdg
flaalrirfdtdspegltpeqlselpqivfgrvipqrvfdelqpvierlrpdlvvqeisn
ygaglaalkagiptichgvgrdtpddltrsieeevrglaqrlgldlppgridgfgnpfid
ifppslqepefrarprrhelrpvpfaeqgdlpawlssrdtarplvyltlgtssggtvevl
raaidglagldadvlvasgpsldvsglgevpanvrleswvpqaallphvdlvvhhggsgt
tlgalgagvpqlsfpwagdsfanaqavaqagagdhllpdnispdsvsgaakrllaeesyr
agaravaaeiaampgpdevvrllpgfas