PDB entry 3mcf

View 3mcf on RCSB PDB site
Description: Crystal structure of human diphosphoinositol polyphosphate phosphohydrolase 3-alpha
Class: hydrolase
Keywords: DIPP3A, NUDT10, APS2, NUDIX, HYDROLASE, diphosphoinositol pentakisphosphate, SIGNAL TRANSDUCTION, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, SGC STOCKHOLM, Metal-binding
Deposited on 2010-03-29, released 2010-04-07
The last revision prior to the SCOPe 2.02 freeze date was dated 2010-04-07, with a file datestamp of 2010-04-02.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.175
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Diphosphoinositol polyphosphate phosphohydrolase 3-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: APS2, DIPP3A, NUDT10
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NFP7 (1-128)
      • expression tag (0)
      • expression tag (129-135)
  • Chain 'B':
    Compound: Diphosphoinositol polyphosphate phosphohydrolase 3-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: APS2, DIPP3A, NUDT10
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NFP7 (1-128)
      • expression tag (0)
    Domains in SCOPe 2.02: d3mcfb_
  • Heterogens: FLC, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3mcfB (B:)
mkkraaclcfrseredevllvsssrypdrwivpgggmepeeepggaavrevyeeagvkgk
lgrllgvfeqnqdpehrtyvyvltvtelledwedsvsigrkrewfkvedaikvlqchkpv
haeyleklkahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3mcfB (B:)
mkkraaclcfrseredevllvsssrypdrwivpgggmepeeepggaavrevyeeagvkgk
lgrllgvfehrtyvyvltvtelledwedsvsigrkrewfkvedaikvlqchkpvhaeyle
klk