PDB entry 3m2r

View 3m2r on RCSB PDB site
Description: Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues
Class: transferase
Keywords: Methyl-Coenzyme M Reductase, Nickel, Metal-binding, Methanogenesis, Methylation, Transferase
Deposited on 2010-03-08, released 2010-09-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methyl-coenzyme M reductase I subunit alpha
    Species: Methanothermobacter marburgensis [TaxId:79929]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3m2ra1, d3m2ra2
  • Chain 'B':
    Compound: Methyl-coenzyme M reductase I subunit beta
    Species: Methanothermobacter marburgensis [TaxId:79929]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3m2rb1, d3m2rb2
  • Chain 'C':
    Compound: Methyl-coenzyme M reductase I subunit gamma
    Species: Methanothermobacter marburgensis [TaxId:79929]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3m2rc_
  • Chain 'D':
    Compound: Methyl-coenzyme M reductase I subunit alpha
    Species: Methanothermobacter marburgensis [TaxId:79929]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3m2rd1, d3m2rd2
  • Chain 'E':
    Compound: Methyl-coenzyme M reductase I subunit beta
    Species: Methanothermobacter marburgensis [TaxId:79929]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3m2re1, d3m2re2
  • Chain 'F':
    Compound: Methyl-coenzyme M reductase I subunit gamma
    Species: Methanothermobacter marburgensis [TaxId:79929]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3m2rf_
  • Heterogens: MG, F43, TP7, COM, TPZ, EDO, ZN, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3m2rA (A:)
adklfinalkkkfeespeekkttfytlggwkqserktefvnagkevaakrgipqynpdig
tplgqrvlmpyqvsttdtyvegddlhfvnnaamqqmwddirrtvivglnhahaviekrlg
kevtpetithyletvnhampgaavvqehmvethpalvadsyvkvftgndeiadeidpafv
idinkqfpedqaetlkaevgdgiwqvvriptivsrtcdgattsrwsamqigmsmisaykq
aageaatgdfayaakhaevihmgtylpvrrargenepggvpfgyladicqssrvnyedpv
rvsldvvatgamlydqiwlgsymsggvgftqyataaytdnilddftyfgkeyvedkyglc
eapnnmdtvldvatevtfygleqyeeypalledqfggsqraavvaaaagcstafatgnaq
tglsgwylsmylhkeqhsrlgfygydlqdqcgasnvfsirgdeglplelrgpnypnyamn
vghqgeyagisqaphaargdafvfnplvkiafaddnlvfdftnvrgefakgalrefepag
eralitpak

    Sequence, based on observed residues (ATOM records): (download) 
    >3m2rA (A:)
adklfinalkkkfeespeekkttfytlggwkqserktefvnagkevaakrgipqynpdig
tplgqrvlmpyqvsttdtyvegddlhfvnnaamqqmwddirrtvivglnhahaviekrlg
kevtpetithyletvnhampgaavvqehmvethpalvadsyvkvftgndeiadeidpafv
idinkqfpedqaetlkaevgdgiwqvvriptivsrtcdgattsrwsamqigmsmisaykq
aageaatgdfayaakhaevihmgtylpvrrargenepggvpfgyladicqssrvnyedpv
rvsldvvatgamlydqiwlgsymsggvgftqyataaytdnilddftyfgkeyvedkyglc
eapnnmdtvldvatevtfygleqyeeypalledqfggsqraavvaaaagcstafatgnaq
tglsgwylsmylhkeqhsrlgfygydlqdqcgasnvfsirgdeglplelrgpnypnyamn
vghqgeyagisqaphaargdafvfnplvkiafaddnlvfdftnvrgefakgalrefepag
eralitpa

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3m2rB (B:)
akfedkvdlyddrgnlveeqvplealsplrnpaiksivqgikrtvavnlegienalktak
vggpackimgreldldivgnaesiaaaakemiqvtedddtnvellgggkralvqvpsarf
dvaaeysaaplvtatafvqaiinefdvsmydanmvkaavlgrypqsveymganiatmldi
pqklegpgyalrnimvnhvvaatlkntlqaaalstileqtamfemgdavgafermhllgl
ayqgmnadnlvfdlvkangkegtvgsviadlveraledgvikvekeltdykvygtddlam
wnayaaaglmaatmvnqgaaraaqgvsstllyyndliefetglpsvdfgkvegtavgfsf
fshsiyggggpgifngnhivtrhskgfaipcvaaamaldagtqmfspeatsglikevfsq
vdefreplkyvveaaaeiknei

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3m2rC (C:)
aqyypgttkvaqnrrnfcnpeyeleklreisdedvvkilghrapgeeypsvhppleemde
pedairemvepidgakagdrvryiqftdsmyfapaqpyvrsraylcryrgadagtlsgrq
iietrerdlekiskelleteffdparsgvrgksvhghslrldedgmmfdmlrrqiynkdt
grvemvknqigdeldepvdlgepldeetlmekttiyrvdgeayrddveaveimqrihvlr
sqggfnle

    Sequence, based on observed residues (ATOM records): (download) 
    >3m2rC (C:)
aqyypgttkvaqnrrnfcnpeyeleklreisdedvvkilghrapgeeypsvhppleemde
pedairemvepidgakagdrvryiqftdsmyfapaqpyvrsraylcryrgadagtlsgrq
iietrerdlekiskelleteffdparsgvrgksvhghslrldedgmmfdmlrrqiynkdt
grvemvknqigdeldepvdlgepldeetlmekttiyrvdgeayrddveaveimqrihvlr
sqggfn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3m2rD (D:)
adklfinalkkkfeespeekkttfytlggwkqserktefvnagkevaakrgipqynpdig
tplgqrvlmpyqvsttdtyvegddlhfvnnaamqqmwddirrtvivglnhahaviekrlg
kevtpetithyletvnhampgaavvqehmvethpalvadsyvkvftgndeiadeidpafv
idinkqfpedqaetlkaevgdgiwqvvriptivsrtcdgattsrwsamqigmsmisaykq
aageaatgdfayaakhaevihmgtylpvrrargenepggvpfgyladicqssrvnyedpv
rvsldvvatgamlydqiwlgsymsggvgftqyataaytdnilddftyfgkeyvedkyglc
eapnnmdtvldvatevtfygleqyeeypalledqfggsqraavvaaaagcstafatgnaq
tglsgwylsmylhkeqhsrlgfygydlqdqcgasnvfsirgdeglplelrgpnypnyamn
vghqgeyagisqaphaargdafvfnplvkiafaddnlvfdftnvrgefakgalrefepag
eralitpak

    Sequence, based on observed residues (ATOM records): (download) 
    >3m2rD (D:)
adklfinalkkkfeespeekkttfytlggwkqserktefvnagkevaakrgipqynpdig
tplgqrvlmpyqvsttdtyvegddlhfvnnaamqqmwddirrtvivglnhahaviekrlg
kevtpetithyletvnhampgaavvqehmvethpalvadsyvkvftgndeiadeidpafv
idinkqfpedqaetlkaevgdgiwqvvriptivsrtcdgattsrwsamqigmsmisaykq
aageaatgdfayaakhaevihmgtylpvrrargenepggvpfgyladicqssrvnyedpv
rvsldvvatgamlydqiwlgsymsggvgftqyataaytdnilddftyfgkeyvedkyglc
eapnnmdtvldvatevtfygleqyeeypalledqfggsqraavvaaaagcstafatgnaq
tglsgwylsmylhkeqhsrlgfygydlqdqcgasnvfsirgdeglplelrgpnypnyamn
vghqgeyagisqaphaargdafvfnplvkiafaddnlvfdftnvrgefakgalrefepag
eralitpa

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3m2rE (E:)
akfedkvdlyddrgnlveeqvplealsplrnpaiksivqgikrtvavnlegienalktak
vggpackimgreldldivgnaesiaaaakemiqvtedddtnvellgggkralvqvpsarf
dvaaeysaaplvtatafvqaiinefdvsmydanmvkaavlgrypqsveymganiatmldi
pqklegpgyalrnimvnhvvaatlkntlqaaalstileqtamfemgdavgafermhllgl
ayqgmnadnlvfdlvkangkegtvgsviadlveraledgvikvekeltdykvygtddlam
wnayaaaglmaatmvnqgaaraaqgvsstllyyndliefetglpsvdfgkvegtavgfsf
fshsiyggggpgifngnhivtrhskgfaipcvaaamaldagtqmfspeatsglikevfsq
vdefreplkyvveaaaeiknei

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3m2rF (F:)
aqyypgttkvaqnrrnfcnpeyeleklreisdedvvkilghrapgeeypsvhppleemde
pedairemvepidgakagdrvryiqftdsmyfapaqpyvrsraylcryrgadagtlsgrq
iietrerdlekiskelleteffdparsgvrgksvhghslrldedgmmfdmlrrqiynkdt
grvemvknqigdeldepvdlgepldeetlmekttiyrvdgeayrddveaveimqrihvlr
sqggfnle

    Sequence, based on observed residues (ATOM records): (download) 
    >3m2rF (F:)
aqyypgttkvaqnrrnfcnpeyeleklreisdedvvkilghrapgeeypsvhppleemde
pedairemvepidgakagdrvryiqftdsmyfapaqpyvrsraylcryrgadagtlsgrq
iietrerdlekiskelleteffdparsgvrgksvhghslrldedgmmfdmlrrqiynkdt
grvemvknqigdeldepvdlgepldeetlmekttiyrvdgeayrddveaveimqrihvlr
sqggfn