PDB entry 3iwp

View 3iwp on RCSB PDB site
Description: Crystal structure of human copper homeostasis protein CutC
Class: metal binding protein
Keywords: Copper homeostasis protein, CutC, conserved sequence motif, metal-binding site, crystal structure, Copper, Polymorphism, METAL BINDING PROTEIN
Deposited on 2009-09-03, released 2009-11-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-11-10, with a file datestamp of 2009-11-06.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.236
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpa_
  • Chain 'B':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpb_
  • Chain 'C':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpc_
  • Chain 'D':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpd_
  • Chain 'E':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpe_
  • Chain 'F':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpf_
  • Chain 'G':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpg_
  • Chain 'H':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwph_
  • Chain 'I':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpi_
  • Chain 'J':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpj_
  • Chain 'K':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpk_
  • Chain 'L':
    Compound: Copper homeostasis protein cutC homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CUTC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3iwpl_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3iwpA (A:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpA (A:)
ngflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmir
prggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvt
fhrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpggg
itdrnlqrilegsgatefhcsarstrdsgmkfrnssvamgaslscseyslkvtdvtkvrt
lnaiaknil

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3iwpB (B:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpB (B:)
ngflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmir
prggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvt
fhrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpggg
itdrnlqrilegsgatefhcsarstrdsgmkfrnssvamgcseyslkvtdvtkvrtlnai
akni

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3iwpC (C:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpC (C:)
ngflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmir
prggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvt
fhrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpggg
itdrnlqrilegsgatefhcsarstrdsgmkfrnssvamgascseyslkvtdvtkvrtln
aiaknil

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3iwpD (D:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpD (D:)
gflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmirp
rggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvtf
hrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpgggi
tdrnlqrilegsgatefhcsarstrdsgmkfrnssvamgscseyslkvtdvtkvrtlnai
aknil

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3iwpE (E:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpE (E:)
ngflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmir
prggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvt
fhrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpggg
itdrnlqrilegsgatefhcsarstrdsgmkfrnssvacseyslkvtdvtkvrtlnaiak
ni

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3iwpF (F:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpF (F:)
gflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmirp
rggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvtf
hrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpgggi
tdrnlqrilegsgatefhcsarstrdsgmkfrnssvamgeyslkvtdvtkvrtlnaiakn
i

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3iwpG (G:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpG (G:)
ngflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmir
prggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvt
fhrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpggg
itdrnlqrilegsgatefhcsarstrdsgmkfrnssyslkvtdvtkvrtlnaiakni

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3iwpH (H:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpH (H:)
gflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmirp
rggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvtf
hrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpgggi
tdrnlqrilegsgatefhcsarstrdsgmkfrnssvslkvtdvtkvrtlnaiakni

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >3iwpI (I:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpI (I:)
ngflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmir
prggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvt
fhrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpggg
itdrnlqrilegsgatefhcsarstrdsgmkfrnssseyslkvtdvtkvrtlnaiaknil
v

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >3iwpJ (J:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpJ (J:)
gflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmirp
rggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvtf
hrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpgggi
tdrnlqrilegsgatefhcsarstrdsgmkfrnssseyslkvtdvtkvrtlnaiaknil

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >3iwpK (K:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpK (K:)
flmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmirpr
ggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvtfh
rafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpgggit
drnlqrilegsgatefhcsarstrdsgmkfrnssvayslkvtdvtkvrtlnaiaknil

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3iwpL (L:)
mrgshhhhhhgsacmkrqgasserkraripsgkagaangflmevcvdsvesavnaergga
drielcsglseggttpsmgvlqvvkqsvqipvfvmirprggdflysdreievmkadirla
klygadglvfgaltedghidkelcmslmaicrplpvtfhrafdmvhdpmaaletlltlgf
ervltsgcdssaleglplikrlieqakgrivvmpgggitdrnlqrilegsgatefhcsar
strdsgmkfrnssvamgaslscseyslkvtdvtkvrtlnaiaknilv

    Sequence, based on observed residues (ATOM records): (download) 
    >3iwpL (L:)
gflmevcvdsvesavnaerggadrielcsglseggttpsmgvlqvvkqsvqipvfvmirp
rggdflysdreievmkadirlaklygadglvfgaltedghidkelcmslmaicrplpvtf
hrafdmvhdpmaaletlltlgfervltsgcdssaleglplikrlieqakgrivvmpgggi
tdrnlqrilegsgatefhcsarstrdsgmkfrnssvayslkvtdvtkvrtlnaiaknil