PDB entry 3ex7
View 3ex7 on RCSB PDB site
Description: The crystal structure of EJC in its transition state
Class: hydrolase/RNA binding protein/RNA
Keywords: PROTEIN-RNA COMPLEX, mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Nucleus, RNA-binding, Spliceosome, Transport, Alternative splicing, Cytoplasm, Phosphoprotein, Acetylation, ATP-binding, Helicase, Hydrolase, Nucleotide-binding, rRNA processing, Coiled coil, hydrolase/RNA binding protein/RNA COMPLEX
Deposited on
2008-10-16, released
2008-12-09
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-01-13, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.207
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Protein mago nashi homolog
Species: Homo sapiens [TaxId:9606]
Gene: MAGOH
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3ex7a_ - Chain 'B':
Compound: RNA-binding protein 8A
Species: Homo sapiens [TaxId:9606]
Gene: RBM8A
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: Eukaryotic initiation factor 4A-III
Species: Homo sapiens [TaxId:9606]
Gene: EIF4A3
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: Protein CASC3
Species: Homo sapiens [TaxId:9606]
Gene: CASC3
Database cross-references and differences (RAF-indexed):
- Chain 'E':
Compound: Protein mago nashi homolog
Species: Homo sapiens [TaxId:9606]
Gene: MAGOH
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3ex7e_ - Chain 'F':
Compound: RNA (5'-r(*up*up*up*up*up*u)-3')
Species: synthetic, synthetic
- Chain 'G':
Compound: RNA-binding protein 8A
Species: Homo sapiens [TaxId:9606]
Gene: RBM8A
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: Eukaryotic initiation factor 4A-III
Species: Homo sapiens [TaxId:9606]
Gene: EIF4A3
Database cross-references and differences (RAF-indexed):
- Chain 'I':
Compound: Protein CASC3
Species: Homo sapiens [TaxId:9606]
Gene: CASC3
Database cross-references and differences (RAF-indexed):
- Chain 'J':
Compound: RNA (5'-r(*up*up*up*up*up*u)-3')
Species: synthetic, synthetic
- Heterogens: ADP, AF3, MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3ex7A (A:)
mesdfylryyvghkgkfgheflefefrpdgklryannsnykndvmirkeayvhksvmeel
kriiddseitkeddalwpppdrvgrqeleivigdehisfttskigslidvnqskdpeglr
vfyylvqdlkclvfsliglhfkikpi
Sequence, based on observed residues (ATOM records): (download)
>3ex7A (A:)
sdfylryyvghkgkfgheflefefrpdgklryannsnykndvmirkeayvhksvmeelkr
iiddseitkeddalwpppdrvgrqeleivigdehisfttskigslidvnqskdpeglrvf
yylvqdlkclvfsliglhfkikpi
- Chain 'B':
No sequence available.
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.
- Chain 'E':
Sequence, based on SEQRES records: (download)
>3ex7E (E:)
mesdfylryyvghkgkfgheflefefrpdgklryannsnykndvmirkeayvhksvmeel
kriiddseitkeddalwpppdrvgrqeleivigdehisfttskigslidvnqskdpeglr
vfyylvqdlkclvfsliglhfkikpi
Sequence, based on observed residues (ATOM records): (download)
>3ex7E (E:)
fylryyvghkgkfgheflefefrpdgklryannsnykndvmirkeayvhksvmeelkrii
ddseitkeddalwpppdrvgrqeleivigdehisfttskigslidvnqskdpeglrvfyy
lvqdlkclvfsliglhfkikpi
- Chain 'F':
No sequence available.
- Chain 'G':
No sequence available.
- Chain 'H':
No sequence available.
- Chain 'I':
No sequence available.
- Chain 'J':
No sequence available.