SCOPe 2.07: Structural Classification of Proteins

PDB entry 2yc8

View 2yc8 on RCSB PDB site
Description: crystal structure of a double mutant (c202a and c222n) of triosephosphate isomerase from giardia lamblia.
Class: isomerase
Keywords: isomerase, glycolysis
Deposited on 2011-03-11, released 2012-03-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-06-05, with a file datestamp of 2013-05-31.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.23523
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8a_
Chain 'B':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8b_
Chain 'C':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8c_
Chain 'D':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8d_
Chain 'E':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8e_
Chain 'F':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8f_
Chain 'G':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8g_
Chain 'H':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8h_
Chain 'I':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8i_
Chain 'J':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8j_
Chain 'K':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8k_
Chain 'L':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8l_
Chain 'M':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8m_
Chain 'N':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8n_
Chain 'O':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8o_
Chain 'P':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8p_
Chain 'Q':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8q_
Chain 'R':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8r_
Chain 'S':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8s_
Chain 'T':
Compound: triosephosphate isomerase
Species: Giardia intestinalis [TaxId:5741]
Database cross-references and differences (RAF-indexed):
- Uniprot P36186 (Start-254)
  - engineered mutation (201)
  - engineered mutation (221)
Domains in SCOPe 2.07: d2yc8t_

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2yc8A (A:)
mparrpfiggnfkcngsldfikshvaaiaahkipdsvdvviapsavhlstaiaantskql
riaaqnvylegngawtgetsvemlqdmglkhvivghserrrimgetdeqsakkakralek
gmtvifcvgetlderkanrtmevniaqlealgkelgeskmlwkevviayepvwsigtgvv
atpeqaeevhvglrkwfaekvaaegaqhiriiyggsangsndeklgqcpnidgflvggas
lkpefmtmidiltkt