PDB entry 2xyf
View 2xyf on RCSB PDB site
Description: HIV-1 Inhibitors with a Tertiary-Alcohol-containing Transition-State Mimic and various P2 and P1 prime Substituents
Class: hydrolase
Keywords: hydrolase, aids
Deposited on
2010-11-17, released
2011-12-07
The last revision prior to the SCOPe 2.07 freeze date was dated
2012-04-04, with a file datestamp of
2012-03-30.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.223
AEROSPACI score: 0.48
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Protease
Species: HUMAN IMMUNODEFICIENCY VIRUS 1 (Z2/CDC-Z34 ISOLATE) [TaxId:11683]
Database cross-references and differences (RAF-indexed):
- Uniprot P03366
- engineered mutation (62)
- engineered mutation (81)
- engineered mutation (83)
Domains in SCOPe 2.07: d2xyfa_ - Chain 'B':
Compound: Protease
Species: HUMAN IMMUNODEFICIENCY VIRUS 1 (Z2/CDC-Z34 ISOLATE) [TaxId:11683]
Database cross-references and differences (RAF-indexed):
- Uniprot P03366 (0-98)
- engineered mutation (62)
- engineered mutation (81)
- engineered mutation (83)
Domains in SCOPe 2.07: d2xyfb_ - Heterogens: G40, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2xyfA (A:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qipieicghkaigtvlvgptptnvigrnlltqigctlnf
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2xyfB (B:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qipieicghkaigtvlvgptptnvigrnlltqigctlnf