PDB entry 2wvh

View 2wvh on RCSB PDB site
Description: Structural insights into the pre-reaction state of pyruvate decarboxylase from Zymomonas mobilis
Class: lyase
Keywords: thiamine diphosphate, lyase, flavoprotein, metal-binding, alcohol fermentation
Deposited on 2009-10-16, released 2010-02-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-06, with a file datestamp of 2019-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wvha1, d2wvha2, d2wvha3
  • Chain 'B':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wvhb1, d2wvhb2, d2wvhb3
  • Chain 'E':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wvhe1, d2wvhe2, d2wvhe3
  • Chain 'F':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wvhf1, d2wvhf2, d2wvhf3
  • Chain 'V':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wvhv1, d2wvhv2, d2wvhv3
  • Chain 'X':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wvhx1, d2wvhx2, d2wvhx3
  • Chain 'Y':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wvhy1, d2wvhy2, d2wvhy3
  • Chain 'Z':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wvhz1, d2wvhz2, d2wvhz3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wvhA (A:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvhA (A:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wvhB (B:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvhB (B:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2wvhE (E:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvhE (E:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2wvhF (F:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvhF (F:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'V':
    Sequence, based on SEQRES records: (download) 
    >2wvhV (V:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvhV (V:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2wvhX (X:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvhX (X:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvn

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >2wvhY (Y:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvhY (Y:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >2wvhZ (Z:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvhZ (Z:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk