PDB entry 2vl3

View 2vl3 on RCSB PDB site
Description: oxidized and reduced forms of human peroxiredoxin 5
Class: oxidoreductase
Keywords: thioredoxin peroxidase, alternative initiation, antioxidant enzyme, redox-active center, cytoplasm, peroxidase, peroxisome, antioxidant, polymorphism, mitochondrion, peroxiredoxin, oxidoreductase, transit peptide, thioredoxin fold
Deposited on 2008-01-08, released 2008-08-26
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.83 Å
R-factor: 0.238
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: peroxiredoxin-5
    Species: HOMO SAPIENS [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VL3 (Start-10)
    • Uniprot P30044 (11-171)
    Domains in SCOPe 2.02: d2vl3a_
  • Chain 'B':
    Compound: peroxiredoxin-5
    Species: HOMO SAPIENS [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VL3
    • Uniprot P30044 (11-171)
    Domains in SCOPe 2.02: d2vl3b_
  • Chain 'C':
    Compound: peroxiredoxin-5
    Species: HOMO SAPIENS [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VL3
    • Uniprot P30044 (11-171)
    Domains in SCOPe 2.02: d2vl3c_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vl3A (A:)
rgshhhhhhgsapikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcsk
thlpgfveqaealkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketd
lllddslvsifgnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql

    Sequence, based on observed residues (ATOM records): (download) 
    >2vl3A (A:)
sapikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcskthlpgfveqa
ealkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketdlllddslvsi
fgnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vl3B (B:)
rgshhhhhhgsapikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcsk
thlpgfveqaealkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketd
lllddslvsifgnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql

    Sequence, based on observed residues (ATOM records): (download) 
    >2vl3B (B:)
apikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcskthlpgfveqae
alkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketdlllddslvsif
gnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2vl3C (C:)
rgshhhhhhgsapikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcsk
thlpgfveqaealkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketd
lllddslvsifgnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql

    Sequence, based on observed residues (ATOM records): (download) 
    >2vl3C (C:)
apikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcskthlpgfveqae
alkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketdlllddslvsif
gnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql