PDB entry 2pz2

View 2pz2 on RCSB PDB site
Description: Crystal structure of the GDP-bound conformation of a G-alpha-i1 mutant with enhanced GTPase activity
Class: hydrolase
Keywords: GTPase, G-PROTEIN, HYDROLYSIS, HYDROLASE
Deposited on 2007-05-17, released 2008-05-27
The last revision prior to the SCOP 1.75 freeze date was dated 2008-05-27, with a file datestamp of 2008-05-23.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.309
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Guanine nucleotide-binding protein G(i), alpha-1 subunit
    Species: HOMO SAPIENS
    Gene: GNAI1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63096 (Start-353)
      • engineered (201)
    Domains in SCOP 1.75: d2pz2a1, d2pz2a2
  • Heterogens: SO4, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pz2A (A:)
mgctlsaedkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheag
yseeeckqykavvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaeegfmt
aelagvikrlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvk
ttgivethftfkdlhfkmfdvagqrserkkwihcfegvtaiifcvalsdydlvlaedeem
nrmhesmklfdsicnnkwftdtsiilflnkkdlfeekikksplticypeyagsntyeeaa
ayiqcqfedlnkrkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf

    Sequence, based on observed residues (ATOM records): (download) 
    >2pz2A (A:)
aaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheagyseeeckqyk
avvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaeegfmtaelagvikrl
wkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvkttgivethft
fkdlhfkmfdvagqrserkkwihcfegvtaiifcvalsdydlvlaedeemnrmhesmklf
dsicnnkwftdtsiilflnkkdlfeekikksplticypeyagsntyeeaaayiqcqfedl
nkrkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf