PDB entry 2pnt

View 2pnt on RCSB PDB site
Description: Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1
Class: structural genomics, unknown function
Keywords: Scaffold protein, Structural Genomics, Structural Genomics Consortium, SGC, UNKNOWN FUNCTION
Deposited on 2007-04-25, released 2007-05-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.21
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: General receptor for phosphoinositides 1-associated scaffold protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GRASP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z6J2 (2-93)
      • see remark 999 (94-97)
    Domains in SCOPe 2.06: d2pnta_
  • Chain 'B':
    Compound: General receptor for phosphoinositides 1-associated scaffold protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GRASP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z6J2 (Start-93)
      • see remark 999 (94-97)
    Domains in SCOPe 2.06: d2pntb_
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pntA (A:)
smqqrkvltlekednqtfgfeiqtyglhhreeqrvemvtfvcrvhesspaqlagltpgdt
iasvnglnvegirhreivdiikasgnvlrletlysstl

    Sequence, based on observed residues (ATOM records): (download) 
    >2pntA (A:)
qqrkvltlekednqtfgfeiqtyglhvemvtfvcrvhesspaqlagltpgdtiasvngln
vegirhreivdiikasgnvlrletlysstl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pntB (B:)
smqqrkvltlekednqtfgfeiqtyglhhreeqrvemvtfvcrvhesspaqlagltpgdt
iasvnglnvegirhreivdiikasgnvlrletlysstl

    Sequence, based on observed residues (ATOM records): (download) 
    >2pntB (B:)
qrkvltlekednqtfgfeiqtyglhhreeqrvemvtfvcrvhesspaqlagltpgdtias
vnglnvegirhreivdiikasgnvlrletlysstl