PDB entry 2nz2

View 2nz2 on RCSB PDB site
Description: Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline
Class: ligase
Keywords: Amino-acid biosynthesis, synthase, aspartate, citrulline, Structural Genomics, Structural Genomics Consortium, SGC, LIGASE
Deposited on 2006-11-22, released 2006-12-05
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.198
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: argininosuccinate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: ASS1, ASS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2nz2a1, d2nz2a2
  • Heterogens: NA, ASP, CIR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2nz2A (A:)
smsskgsvvlaysggldtscilvwlkeqgydviaylanigqkedfeearkkalklgakkv
fiedvsrefveefiwpaiqssalyedryllgtslarpciarkqveiaqregakyvshgat
gkgndqvrfelscyslapqikviapwrmpefynrfkgrndlmeyakqhgipipvtpknpw
smdenlmhisyeagilenpknqappglytktqdpakapntpdileiefkkgvpvkvtnvk
dgtthqtslelfmylnevagkhgvgridivenrfigmksrgiyetpagtilyhahldiea
ftmdrevrkikqglglkfaelvytgfwhspecefvrhciaksqervegkvqvsvlkgqvy
ilgresplslyneelvsmnvqgdyeptdatgfininslrlkeyhrlqskvtak

    Sequence, based on observed residues (ATOM records): (download) 
    >2nz2A (A:)
kgsvvlaysggldtscilvwlkeqgydviaylanigqkedfeearkkalklgakkvfied
vsrefveefiwpaiqssalyedryllgtslarpciarkqveiaqregakyvshgatgkgn
dqvrfelscyslapqikviapwrmpefynrfkrndlmeyakqhgipipvtpknpwsmden
lmhisyeagilenpknqappglytktqdpakapntpdileiefkkgvpvkvtnvkdgtth
qtslelfmylnevagkhgvgridivenrfigmksrgiyetpagtilyhahldieaftmdr
evrkikqglglkfaelvytgfwhspecefvrhciaksqervegkvqvsvlkgqvyilgre
splslyneelvsnvqgdyeptdatgfininslrlkeyhrlqs