PDB entry 2jga

View 2jga on RCSB PDB site
Description: crystal structure of human cytosolic 5'-nucleotidase III in complex with phosphate and magnesium
Class: hydrolase
Keywords: pyrimidine 5-prime- nucleotidase 1, nucleotide metabolism, pyrimidine 5-prime nucleotidase deficiency, uridine 5-prime monophosphate hydrolase 1, cytosolic III, disease mutation, nucleotide-binding, p5n1, umph1, 5-prime, hydrolase, nucleotidase
Deposited on 2007-02-09, released 2007-04-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 3.01 Å
R-factor: 0.185
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytosolic 5'-nucleotidase III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JGA
      • conflict (77)
    • Uniprot Q9H0P0 (19-291)
    Domains in SCOPe 2.07: d2jgaa_
  • Heterogens: PO4, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2jgaA (A:)
mgsshhhhhhssglvprgsnptrveeiicglikggaaklqiitdfdmtlsrfsykgkrcp
tchniidncklvtdecrrkllqlkekyyaievdpvltveekypymvewytkshgllvqqa
lpkaklkeivaesdvmlkegyenffdklqqhsipvfifsagigdvleevirqagvyhpnv
kvvsnfmdfdetgvlkgfkgelihvfnkhdgalrnteyfnqlkdnsniillgdsqgdlrm
adgvanvehilkigylndrvdellekymdsydivlvqdeslevansilqkil

    Sequence, based on observed residues (ATOM records): (download) 
    >2jgaA (A:)
nptrveeiicglikggaaklqiitdfdmtlsrfsykgkrcptchniidncklvtdecrrk
llqlkekyyaievdpvltveekypymvewytkshgllvqqalpkaklkeivaesdvmlke
gyenffdklqqhsipvfifsagigdvleevirqagvyhpnvkvvsnfmdfdetgvlkgfk
gelihvfnkhdgalrnteyfnqlkdnsniillgdsqgdlrmadgvanvehilkigylndr
vdellekymdsydivlvqdeslevansilqkil