PDB entry 2hq5

View 2hq5 on RCSB PDB site
Description: Crystal structure of multidrug binding protein QacR from Staphylococcus aureus cocrystallized with compound DB359
Class: transcription
Keywords: multidrug recognition, db359, qacr, multidrug binding protein, transcription
Deposited on 2006-07-18, released 2007-07-17
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.213
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: QacR, SAVP031
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • engineered (71)
      • engineered (140)
    Domains in SCOPe 2.02: d2hq5a1, d2hq5a2
  • Chain 'B':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: QacR, SAVP031
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • engineered (71)
      • engineered (140)
    Domains in SCOPe 2.02: d2hq5b1, d2hq5b2
  • Chain 'D':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: QacR, SAVP031
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • engineered (71)
      • engineered (140)
    Domains in SCOPe 2.02: d2hq5d1, d2hq5d2
  • Chain 'E':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: QacR, SAVP031
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • engineered (71)
      • engineered (140)
    Domains in SCOPe 2.02: d2hq5e1, d2hq5e2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2hq5A (A:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2hq5A (A:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2hq5B (B:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2hq5B (B:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsnekmnklenk
yidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqif
lngls

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2hq5D (D:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2hq5D (D:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2hq5E (E:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2hq5E (E:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngl