PDB entry 2gho

View 2gho on RCSB PDB site
Description: Recombinant Thermus aquaticus RNA polymerase for Structural Studies
Class: transferase
Keywords: Thermus aquaticus RNA polymerase, recombinant multiprotein complex, coexpression, TRANSFERASE
Deposited on 2006-03-27, released 2006-05-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 5 Å
R-factor: N/A
AEROSPACI score: -0.05 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-directed RNA polymerase subunit alpha
    Species: Thermus aquaticus [TaxId:271]
    Gene: rpoA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2ghoa1, d2ghoa2
  • Chain 'B':
    Compound: DNA-directed RNA polymerase subunit alpha
    Species: Thermus aquaticus [TaxId:271]
    Gene: rpoA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2ghob1, d2ghob2
  • Chain 'C':
    Compound: DNA-directed RNA polymerase subunit beta
    Species: Thermus aquaticus [TaxId:271]
    Gene: rpoB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2ghoc1
  • Chain 'D':
    Compound: DNA-directed RNA polymerase subunit beta',DNA-directed RNA polymerase subunit beta'
    Species: Thermus aquaticus [TaxId:271]
    Gene: rpoC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KWU6 (Start-157)
      • linker (158-159)
    • Uniprot Q9KWU6 (160-End)
    Domains in SCOPe 2.07: d2ghod1

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ghoA (A:)
mlesklkapvftattqgdhygefvleplergfgvtlgnplrrillssipgtavtsvyied
vlhefstipgvkedvveiilnlkelvvrfldpkmasttlilraegpkevragdftpsadv
eimnpdlhiatleeggklymevrvdrgvgyvpaerhgikdrinaipvdaifspvrrvafq
vedtrlgqrtdldkltlriwtdgsvtplealnqavailkehlnyfanpeasllptpevsk
gekresaeedldlpleelglstrvlhslkeegiesvrallalnlkdlrnipgigerslee
irqalakkgftlke

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghoA (A:)
lkapvftattqgdhygefvleplergfgvtlgnplrrillssipgtavtsvyiedvlhef
stipgvkedvveiilnlkelvvrfldpkmasttlilraegpkevragdftpsadveimnp
dlhiatleeggklymevrvdrgvgyvpaerhgikdrinaipvdaifspvrrvafqvedtr
lgqrtdldkltlriwtdgsvtplealnqavailkehlnyfanpeasllpt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ghoB (B:)
mlesklkapvftattqgdhygefvleplergfgvtlgnplrrillssipgtavtsvyied
vlhefstipgvkedvveiilnlkelvvrfldpkmasttlilraegpkevragdftpsadv
eimnpdlhiatleeggklymevrvdrgvgyvpaerhgikdrinaipvdaifspvrrvafq
vedtrlgqrtdldkltlriwtdgsvtplealnqavailkehlnyfanpeasllptpevsk
gekresaeedldlpleelglstrvlhslkeegiesvrallalnlkdlrnipgigerslee
irqalakkgftlke

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghoB (B:)
sklkapvftattqgdhygefvleplergfgvtlgnplrrillssipgtavtsvyiedvlh
efstipgvkedvveiilnlkelvvrfldpkmasttlilraegpkevragdftpsadveim
npdlhiatleeggklymevrvdrgvgyvpaerhgikdrinaipvdaifspvrrvafqved
trlgqrtdldkltlriwtdgsvtplealnqavailkehlnyfanp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2ghoC (C:)
meikrfgrireviplpplteiqvesykkalqadvppekrenvgiqaafketfpieegdkg
kgglvldfleyrigdppfsqdecrekdltyqaplyarlqlihkdtglikedevflghlpl
mtedgsfiingadrvivsqihrspgvyftpdparpgryiasiiplpkrgpwidleveasg
vvtmkvnkrkfplvlllrvlgydqetlvrelsaygdlvqglldeavlamrpeeamvrlft
llrpgdppkkdkalaylfglladpkrydlgeagrykaeeklgvglsgrtlvrfedgefkd
evflptlrylfaltagvpghevddidhlgnrrirtvgelmadqfrvglarlargvrermv
mgspdtltpaklvnsrpleaalreffsrsqlsqfkdetnplsslrhkrrisalgpggltr
eragfdvrdvhrthygricpvetpeganiglitslaayarvdalgfirtpyrrvkngvvt
eevvymtaseedrytiaqantplegdriatdrvvarrrgepvivapeevefmdvspkqvf
slntnlipflehddanralmgsnmqtqavpliraqapvvmtgleervvrdslaalyaeed
gevvkvdgtriavryedgrlvehplrryarsnqgtafdqrprvrvgqrvkkgdlladgpa
seegflalgqnvlvaimpfdgynfedaiviseellkrdfytsihieryeieardtklgpe
ritrdiphlseaalrdldeegivrigaevkpgdilvgrtsfkgeqepspeerllrsifge
kardvkdtslrvppgeggivvgrlrlrrgdpgvelkpgvrevvrvfvaqkrklqvgdkla
nrhgnkgvvakilpvedmphlpdgtpvdvilnplgvpsrmnlgqilethlglagyflgqr
yispvfdgatepeikellaeafnlyfgkrqgegfgvdkrekevlaraeklglvspgkspe
eqlkelfdlgkvvlydgrtgepfegpivvgqmfimklyhmvedkmharstgpyslitqqp
lggkaqfggqrfgemevwaleaygaahtlqemltiksddiegrnaayqaiikgedvpeps
vpesfrvlvkelqalaldvqtldekdnpvdifeglaskr

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghoC (C:)
meikrfgrireviplpplteiqvesykkalqadvppekrenvgiqaafketfpieegdkg
kgglvldfleyrigdppfsqdecrekdltyqaplyarlqlihkdtglikedevflghlpl
mtedgsfiingadrvivsqihrspgvyftpdparpgryiasiiplpkrgpwidleveasg
vvtmkvnkrkfplvlllrvlgydqetlvrelsaygdlvqglldeavlamrpeeamvrlft
llrpgdppkkdkalaylfglladpkrydlgeagrykaeeklgvglsgrtlvrfedgefkd
evflptlrylfaltagvpghevddidhlgnrrirtvgelmadqfrvglarlargvrermv
mgspdtltpaklvnsrpleaalreffsrsqlsqfkdetnplsslrhkrrisalgpggltr
eragfdvrdvhrthygricpvetpeganiglitslaayarvdalgfirtpyrrvkngvvt
eevvymtaseedrytiaqantplegdriatdrvvarrrgepvivapeevefmdvspkqvf
slntnlipflehddanralmgsnmqtqavpliraqapvvmtgleervvrdslaalyaeed
gevvkvdgtriavryedgrlvehplrryarsnqgtafdqrprvrvgqrvkkgdlladgpa
seegflalgqnvlvaimpfdgynfedaiviseellkrdfytsihieryeieardtklgpe
ritrdiphlseaalrdldeegivrigaevkpgdilvgrtsfkgeqepspeerllrsifge
kardvkdtslrvppgeggivvgrlrlrrgdpgvelkpgvrevvrvfvaqkrklqvgdkla
nrhgnkgvvakilpvedmphlpdgtpvdvilnplgvpsrmnlgqilethlglagyflgqr
yispvfdgatepeikellaeafnlyfgkrqgegfgvdkrekevlaraeklglvspgkspe
eqlkelfdlgkvvlydgrtgepfegpivvgqmfimklyhmvedkmharstgpyslitqqp
lggkaqfggqrfgemevwaleaygaahtlqemltiksddiegrnaayqaiikgedvpeps
vpesfrvlvkelqalaldvqtldekdnpvdifeg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2ghoD (D:)
mkkevrkvrialaspekirswsygevekpetinyrtlkperdglfderifgpikdyecac
gkykrqrfegkvcercgvevtrsivrryrmghielatpaahiwfvkdvpskigtlldlsa
teleqvlyfnkyivldpkgavldgvpvekrqlltdeeyggidarmgaeaiqellkeldle
klerelleemkhpsrarrakarkrlevvrafldsgnrpewmileavpvlppdlrpmvqvd
ggrfatsdlndlyrrlinrnnrlkkllaqgapeiiirnekrmlqeavdavidngrrgspv
tnpgserplrsltdilsgkqgrfrqnllgkrvdysgrsvivvgpqlklhqcglpkrmale
lfkpfllkkmeekafapnvkaarrmlerqrdikdevwdaleevihgkvvllnraptlhrl
giqafqpvlvegqsiqlhplvceafnadfdgdqmavhvplssfaqaeariqmlsahnlls
pasgeplakpsrdiilglyyitqvrkekkgagmafatpeealaayergevalnapivvag
retsvgrlkfvfanpdeallavahglldlqdvvtvrylgrrletspgrilfarivgeavg
dekvaqeliqmdvpqeknslkdlvyqaflrlgmektarlldalkyygftlsttsgitigi
ddavipeekqryleeadrklrqieqayemgfltdrerydqviqlwtettekvtqavfknf
eenypfnplyvmaqsgargnpqqirqlcgmrglmqkpsgetfevpvrssfregltvleyf
isshgarkggadtalrtadsgyltrklvdvaheivvreadcgttnyisvplfqmdevtrt
lrlrkrsdiesglygrvlarevealgrrleegrylsledvhflikaaeagevrevpvrsp
ltcqtrygvcqkcygydlsmarpvsigeavgvvaaesigepgtqltmrtfhtggvavgtd
itqglprvielfearrpkakaviseidgvvrieegedrlsvfvesegfskeyklpkdarl
lvkdgdyveagqpltrgaidphqlleakgpeaverylvdeiqkvyraqgvklhdkhieiv
vrqmlkyvevtdpgdsrllegqvlekwdvealnerliaegkvpvawkpllmgvtksalst
kswlsaasfqntthvlteaaiagkkdeliglkenvilgrlipagtgsdfvrftqvvdqrt
lkaieearkeaveakekeaprrpvrreqpgkgl

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghoD (D:)
kevrkvrialaspekirswsygevekpetinyrtlkperdglfderifgpikdyecacgk
ykrqrfegkvcercgvevtrsivrryrmghielatpaahiwfvkdvpskigtlldlsate
leqvlyfnkyivldpkgavldgvpvekrqlltdeeyggidarmgaeaiqellkeldlekl
erelleemkhpsrarrakarkrlevvrafldsgnrpewmileavpvlppdlrpmvqvdgg
rfatsdlndlyrrlinrnnrlkkllaqgapeiiirnekrmlqeavdavidngrrgspvtn
pgserplrsltdilsgkqgrfrqnllgkrvdysgrsvivvgpqlklhqcglpkrmalelf
kpfllkkmeekafapnvkaarrmlerqrdikdevwdaleevihgkvvllnraptlhrlgi
qafqpvlvegqsiqlhplvceafnadfdgdqmavhvplssfaqaeariqmlsahnllspa
sgeplakpsrdiilglyyitqvrkekkgagmafatpeealaayergevalnapivvagre
tsvgrlkfvfanpdeallavahglldlqdvvtvrylgrrletspgrilfarivgeavgde
kvaqeliqmdvpqeknslkdlvyqaflrlgmektarlldalkyygftlsttsgitigidd
avipeekqryleeadrklrqieqayemgfltdrerydqviqlwtettekvtqavfknfee
nypfnplyvmaqsgargnpqqirqlcgmrglmqkpsgetfevpvrssfregltvleyfis
shgarkggadtalrtadsgyltrklvdvaheivvreadcgttnyisvplfqmdevtrtlr
lrkrsdiesglygrvlarevealgrrleegrylsledvhflikaaeagevrevpvrsplt
cqtrygvcqkcygydlsmarpvsigeavgvvaaesigepgtqltmrttqglprvielfea
rrpkakaviseidgvvrieegedrlsvfvesegfskeyklpkdarllvkdgdyveagqpl
trgaidphqlleakgpeaverylvdeiqkvyraqgvklhdkhieivvrqmlkyvevtdpg
dsrllegqvlekwdvealnerliaegkvpvawkpllmgvtksalstkswlsaasfqntth
vlteaaiagkkdeliglkenvilgrlipagtgsdfvrftqvvdqrtlkaieearke