SCOPe 2.05: Structural Classification of Proteins

PDB entry 2e7s

View 2e7s on RCSB PDB site
Description: Crystal structure of the yeast Sec2p GEF domain
Class: endocytosis/exocytosis
Keywords: coiled coil, endocytosis/exocytosis complex
Deposited on 2007-01-12, released 2007-02-27
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-06-02, with a file datestamp of 2009-05-29.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.229
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sa1
Chain 'B':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sb_
Chain 'C':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sc_
Chain 'D':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sd_
Chain 'E':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7se_
Chain 'F':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sf_
Chain 'G':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sg_
Chain 'H':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sh_
Chain 'I':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7si_
Chain 'J':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sj_
Chain 'K':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sk_
Chain 'L':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sl_
Chain 'M':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sm_
Chain 'N':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sn_
Chain 'O':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7so_
Chain 'P':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sp_
Chain 'Q':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sq_
Chain 'R':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7sr_
Chain 'S':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7ss_
Chain 'T':
Compound: Rab guanine nucleotide exchange factor SEC2
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P17065 (5-End)
  - engineered (89)
Domains in SCOPe 2.05: d2e7st_
Heterogens: HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2e7sA (A:)
gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
tltlqlknlkkvmhs