PDB entry 2e7s

View 2e7s on RCSB PDB site
Description: Crystal structure of the yeast Sec2p GEF domain
Class: endocytosis/exocytosis
Keywords: coiled coil, endocytosis/exocytosis complex
Deposited on 2007-01-12, released 2007-02-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-06-02, with a file datestamp of 2009-05-29.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.229
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sa1
  • Chain 'B':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sb_
  • Chain 'C':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sc_
  • Chain 'D':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sd_
  • Chain 'E':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7se_
  • Chain 'F':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sf_
  • Chain 'G':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sg_
  • Chain 'H':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sh_
  • Chain 'I':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7si_
  • Chain 'J':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sj_
  • Chain 'K':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sk_
  • Chain 'L':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sl_
  • Chain 'M':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sm_
  • Chain 'N':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sn_
  • Chain 'O':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7so_
  • Chain 'P':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sp_
  • Chain 'Q':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sq_
  • Chain 'R':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7sr_
  • Chain 'S':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7ss_
  • Chain 'T':
    Compound: Rab guanine nucleotide exchange factor SEC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17065 (5-End)
      • engineered (89)
    Domains in SCOPe 2.08: d2e7st_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2e7sA (A:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sA (A:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmll
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2e7sB (B:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sB (B:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlldtltlq
    l
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2e7sC (C:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sC (C:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlldtlt
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2e7sD (D:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sD (D:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlldtltlq
    lknl
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >2e7sE (E:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sE (E:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlldtltlq
    lknl
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >2e7sF (F:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sF (F:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlldtltlq
    lknl
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >2e7sG (G:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sG (G:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrek
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >2e7sH (H:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sH (H:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteql
    

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >2e7sI (I:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sI (I:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmll
    

  • Chain 'J':
    Sequence, based on SEQRES records: (download)
    >2e7sJ (J:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sJ (J:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteql
    

  • Chain 'K':
    Sequence, based on SEQRES records: (download)
    >2e7sK (K:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sK (K:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlldtl
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2e7sL (L:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sL (L:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmll
    

  • Chain 'M':
    Sequence, based on SEQRES records: (download)
    >2e7sM (M:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sM (M:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlldtl
    

  • Chain 'N':
    Sequence, based on SEQRES records: (download)
    >2e7sN (N:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sN (N:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekd
    

  • Chain 'O':
    Sequence, based on SEQRES records: (download)
    >2e7sO (O:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sO (O:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlldtltlq
    lknl
    

  • Chain 'P':
    Sequence, based on SEQRES records: (download)
    >2e7sP (P:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sP (P:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmll
    

  • Chain 'Q':
    Sequence, based on SEQRES records: (download)
    >2e7sQ (Q:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sQ (Q:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekd
    

  • Chain 'R':
    Sequence, based on SEQRES records: (download)
    >2e7sR (R:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sR (R:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekd
    

  • Chain 'S':
    Sequence, based on SEQRES records: (download)
    >2e7sS (S:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sS (S:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlldtl
    

  • Chain 'T':
    Sequence, based on SEQRES records: (download)
    >2e7sT (T:)
    gplgsleeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakene
    lrtkaeeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmlld
    tltlqlknlkkvmhs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2e7sT (T:)
    leeqlnkslktiasqkaaienynqlkedyntlkrelsdrddevkrlrediakenelrtka
    eeeadklnkevedltaslfdeannlvadarmekyaieilnkrlteqlrekdmll