PDB entry 2co0

View 2co0 on RCSB PDB site
Description: wdr5 and unmodified histone h3 complex at 2.25 angstrom
Class: transcription
Keywords: transcription, histone presenter, lysine methylation, mll1, leukemia, hox gene activation, transcription activation
Deposited on 2006-05-25, released 2006-07-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.19
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: wd-repeat protein 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61964 (Start-314)
      • conflict (18)
      • conflict (142)
      • conflict (217)
      • conflict (262)
    Domains in SCOPe 2.04: d2co0a_
  • Chain 'B':
    Compound: histone h3 dimethyl-lysine 4
    Database cross-references and differences (RAF-indexed):
    • PDB 2CO0 (0-End)
  • Chain 'C':
    Compound: wd-repeat protein 5
    Species: Homo sapiens [TaxId:9606]
    Domains in SCOPe 2.04: d2co0c_
  • Chain 'D':
    Compound: histone h3 dimethyl-lysine 4
    Database cross-references and differences (RAF-indexed):
    • PDB 2CO0 (0-End)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2co0A (A:)
sssatqskptpvkpnyalmftlaghtkavssvkfspngewlasssadklikiwgaydgkf
ektisghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnp
qsnlivsgsfdesvriwdvktgmclktlpahsdpvsavhfnrdgslivsssydglcriwd
tasgqclktlidddnppvsfvkfspngkyilaatldndlklwdyskgkclktytghknek
ycifanfsvtggkwivsgsednmvyiwnlqtkeivqklqghtdvvistachpteniiasa
alendktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >2co0A (A:)
vkpnyalmftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklgi
sdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsfd
esvriwdvktgmclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktli
dddnppvsfvkfspngkyilaatldndlklwdyskgkclktytghknekycifanfsvtg
gkwivsgsednmvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktiklw
ksdc

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2co0C (C:)
sssatqskptpvkpnyalmftlaghtkavssvkfspngewlasssadklikiwgaydgkf
ektisghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnp
qsnlivsgsfdesvriwdvktgmclktlpahsdpvsavhfnrdgslivsssydglcriwd
tasgqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknek
ycifanfsvtggkwivsgsednmvyiwnlqtkeivqklqghtdvvistachpteniiasa
alendktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >2co0C (C:)
vkpnyalmftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklgi
sdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsfd
esvriwdvktgmclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktli
dddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsvtg
gkwivsgsednmvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktiklw
ksdc

  • Chain 'D':
    No sequence available.