PDB entry 2bhg

View 2bhg on RCSB PDB site
Description: 3c protease from type a10(61) foot-and-mouth disease virus
Class: hydrolase
Keywords: foot-and-mouth disease virus, protease, chymotrypsin-like cysteine protease, capsid protein, core protein, covalent protein-RNA linkage, hydrolase, lipoprotein, myristate, polyprotein, RNA-directed RNA polymerase, thiol protease, transferase
Deposited on 2005-01-10, released 2005-02-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.218
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: foot-and-mouth disease virus 3c protease
    Species: FOOT-AND-MOUTH DISEASE VIRUS [TaxId:12110]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BHG
      • engineered mutation (95)
      • engineered mutation (163)
      • conflict see remark 9 (78-89)
    • Uniprot P03306 (90-End)
    Domains in SCOPe 2.08: d2bhga1
  • Chain 'B':
    Compound: foot-and-mouth disease virus 3c protease
    Species: FOOT-AND-MOUTH DISEASE VIRUS [TaxId:12110]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BHG
      • engineered mutation (95)
      • engineered mutation (163)
      • conflict see remark 9 (82-89)
    • Uniprot P03306 (90-End)
    Domains in SCOPe 2.08: d2bhgb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bhgA (A:)
gsgapptdlqkmvmgntkpvelnldgktvaiccatgvfgtaylvprhlfaekydkimldg
ramtdsdyrvfefeikvkgqdmlsdaalmvlhrgnkvrditkhfrdtarmkkgtpvvgvv
nnadvgrlifsgealtykdivvsmdgdtmpglfaykaatragyaggavlakdgadtfivg
thsaggngvgycscvsrsmlqkmkahveh

    Sequence, based on observed residues (ATOM records): (download) 
    >2bhgA (A:)
dlqkmvmgntkpvelnldgktvaiccatgvfgtaylvprhlfaekydkimldgramtdsd
yrvfefeikvkgqdmlsdaalmvlhrgnkvrditkhfrdtarmkkgtpvvgvvnnadvgr
lifsgealtykdivvtmpglfaykaatragyaggavlakdgadtfivgthsaggngvgyc
scvsrsmlqkmkah

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2bhgB (B:)
gsgapptdlqkmvmgntkpvelnldgktvaiccatgvfgtaylvprhlfaekydkimldg
ramtdsdyrvfefeikvkgqdmlsdaalmvlhrgnkvrditkhfrdtarmkkgtpvvgvv
nnadvgrlifsgealtykdivvsmdgdtmpglfaykaatragyaggavlakdgadtfivg
thsaggngvgycscvsrsmlqkmkahveh

    Sequence, based on observed residues (ATOM records): (download) 
    >2bhgB (B:)
dlqkmvmgntkpvelnldgktvaiccatgvfgtaylvprhlfaekydkimldgramtdsd
yrvfefelsdaalmvlhrgnkvrditkhfrdtarmkkgtpvvgvvnnadvgrlifsgeal
tykdivmpglfaykaatragyaggavlakdgadtfivgthsaggngvgycscvsrsmlqk
mkah