PDB entry 1zos

View 1zos on RCSB PDB site
Description: Structure of 5'-methylthionadenosine/S-Adenosylhomocysteine nucleosidase from S. pneumoniae with a transition-state inhibitor MT-ImmA
Class: hydrolase
Keywords: nucleosidase, pneumoniae, transition state, inhibitor, HYDROLASE
Deposited on 2005-05-13, released 2006-04-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-09-22, with a file datestamp of 2009-09-18.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.193
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1zosa_
  • Chain 'B':
    Compound: 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1zosb_
  • Chain 'C':
    Compound: 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1zosc_
  • Chain 'D':
    Compound: 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1zosd_
  • Chain 'E':
    Compound: 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1zose_
  • Chain 'F':
    Compound: 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1zosf_
  • Heterogens: MTM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1zosA (A:)
    mkigiiaampeelaylvqhldntqeqvvlgntyhtgtiashevvlvesgigkvmsamsva
    iladhfqvdalintgsagavaegiavgdvviadklayhdvdvtafgyaygqmaqqplyfe
    sdktfvaqiqeslsqldqnwhlgliatgdsfvagndkieaikshfpevlavemegaaiaq
    aahtlnlpvlviramsdnanheaniffdefiieagrrsaqvllaflkald
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1zosB (B:)
    mkigiiaampeelaylvqhldntqeqvvlgntyhtgtiashevvlvesgigkvmsamsva
    iladhfqvdalintgsagavaegiavgdvviadklayhdvdvtafgyaygqmaqqplyfe
    sdktfvaqiqeslsqldqnwhlgliatgdsfvagndkieaikshfpevlavemegaaiaq
    aahtlnlpvlviramsdnanheaniffdefiieagrrsaqvllaflkald
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1zosC (C:)
    mkigiiaampeelaylvqhldntqeqvvlgntyhtgtiashevvlvesgigkvmsamsva
    iladhfqvdalintgsagavaegiavgdvviadklayhdvdvtafgyaygqmaqqplyfe
    sdktfvaqiqeslsqldqnwhlgliatgdsfvagndkieaikshfpevlavemegaaiaq
    aahtlnlpvlviramsdnanheaniffdefiieagrrsaqvllaflkald
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1zosD (D:)
    mkigiiaampeelaylvqhldntqeqvvlgntyhtgtiashevvlvesgigkvmsamsva
    iladhfqvdalintgsagavaegiavgdvviadklayhdvdvtafgyaygqmaqqplyfe
    sdktfvaqiqeslsqldqnwhlgliatgdsfvagndkieaikshfpevlavemegaaiaq
    aahtlnlpvlviramsdnanheaniffdefiieagrrsaqvllaflkald
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1zosE (E:)
    mkigiiaampeelaylvqhldntqeqvvlgntyhtgtiashevvlvesgigkvmsamsva
    iladhfqvdalintgsagavaegiavgdvviadklayhdvdvtafgyaygqmaqqplyfe
    sdktfvaqiqeslsqldqnwhlgliatgdsfvagndkieaikshfpevlavemegaaiaq
    aahtlnlpvlviramsdnanheaniffdefiieagrrsaqvllaflkald
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1zosF (F:)
    mkigiiaampeelaylvqhldntqeqvvlgntyhtgtiashevvlvesgigkvmsamsva
    iladhfqvdalintgsagavaegiavgdvviadklayhdvdvtafgyaygqmaqqplyfe
    sdktfvaqiqeslsqldqnwhlgliatgdsfvagndkieaikshfpevlavemegaaiaq
    aahtlnlpvlviramsdnanheaniffdefiieagrrsaqvllaflkald