PDB entry 1xfb

View 1xfb on RCSB PDB site
Description: Human Brain Fructose 1,6-(bis)phosphate Aldolase (C isozyme)
Class: lyase
Keywords: isozyme specificity, structural enzymology, protein-protein interactions, isozyme specific residues, structure/function, LYASE
Deposited on 2004-09-14, released 2005-02-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.255
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfba1
  • Chain 'B':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbb_
  • Chain 'C':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbc_
  • Chain 'D':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbd_
  • Chain 'E':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbe_
  • Chain 'F':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbf_
  • Chain 'G':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbg_
  • Chain 'H':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbh_
  • Chain 'I':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbi_
  • Chain 'J':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbj_
  • Chain 'K':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbk_
  • Chain 'L':
    Compound: Aldolase C
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xfbl_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1xfbA (A:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbA (A:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1xfbB (B:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbB (B:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1xfbC (C:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbC (C:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1xfbD (D:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbD (D:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1xfbE (E:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbE (E:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1xfbF (F:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbF (F:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1xfbG (G:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbG (G:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1xfbH (H:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbH (H:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1xfbI (I:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbI (I:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1xfbJ (J:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbJ (J:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1xfbK (K:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbK (K:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1xfbL (L:)
mphsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyr
qvlfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtd
getttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghac
pikytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltf
sygralqasalnawrgqrdnagaateefikraevnglaaqgkyegsgedggaaaqslyia
nhayl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xfbL (L:)
hsypalsaeqkkelsdialrivapgkgilaadesvgsmakrlsqigventeenrrlyrqv
lfsaddrvkkciggviffhetlyqkddngvpfvrtiqdkgivvgikvdkgvvplagtdge
tttqgldglsercaqykkdgadfakwrcvlkisertpsalailenanvlaryasicqqng
ivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhvylegtllkpnmvtpghacpi
kytpeeiamatvtalrrtvppavpgvtflsggqseeeasfnlnainrcplprpwaltfsy
gralqasalnawrgqrdnagaateefikraevnglaaqgkye