PDB entry 1rke

View 1rke on RCSB PDB site
Description: Human vinculin head (1-258) in complex with human vinculin tail (879-1066)
Class: cell adhesion, structural protein
Keywords: cytoskeleton; actin-binding; x-ray crystallography, cell adhesion, structural protein
Deposited on 2003-11-21, released 2004-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-19.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.206
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: vinculin
    Species: Homo sapiens [TaxId:9606]
    Gene: VCL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18206 (4-261)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d1rkea1, d1rkea2, d1rkea3
  • Chain 'B':
    Compound: VCL protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1rkeb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rkeA (A:)
hhhhmpvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnlvr
vgketvqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgil
sgtsdllltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmid
erqqelthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvek
msaeineiirvlqltswdedaw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1rkeB (B:)
deefpeqkagevinqpmmmaarqlhdearkwsskgndiiaaakrmallmaemsrlvrggs
gtkraliqcakdiakasdevtrlakevakqctdkrirtnllqvceriptistqlkilstv
katmlgrtnisdeeseqatemlvhnaqnlmqsvketvreaeaasikirtdagftlrwvrk
tpwyq

    Sequence, based on observed residues (ATOM records): (download) 
    >1rkeB (B:)
deefpeqkagevinqpmmmaarqlhdearkwsskgndiiaaakrmallmaemsrlvrggs
gtkraliqcakdiakasdevtrlakevakqctdkrirtnllqvceriptistqlkilstv
katmldeeseqatemlvhnaqnlmqsvketvreaeaasikirtdagftlrwvrktp