PDB entry 1n3a

View 1n3a on RCSB PDB site
Description: Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase
Class: hydrolase, lyase/DNA
Keywords: HhH-GPD, glycosylase, DNA-repair, oxoguanine, hydrolase, lyase/DNA COMPLEX
Deposited on 2002-10-25, released 2003-03-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.24
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N-glycosylase/DNA lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: OGG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15527 (3-316)
      • cloning artifact (0-2)
      • engineered (259)
    Domains in SCOPe 2.06: d1n3aa1, d1n3aa2, d1n3aa3
  • Chain 'B':
    Compound: DNA complement strand
  • Chain 'C':
    Compound: DNA inhibitor strand
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1n3aA (A:)
gseghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladqvwtltq
teeqlhctvyrgdksqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqevaqkfq
gvrllrqdpieclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpslqala
gpeveahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalcilpgvgt
kvadciclmaldkpqavpvqvhmwhiaqrdyswhpttsqakgpspqtnkelgnffrslwg
pyagwaqavlfsadlrq

    Sequence, based on observed residues (ATOM records): (download) 
    >1n3aA (A:)
gseghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladqvwtltq
teeqlhctvyrsqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqevaqkfqgvr
llrqdpieclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpslqalagpe
veahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalcilpgvgtkva
dciclmaldkpqavpvqvhmwhiaqrdyswhpttsqakgpspqtnkelgnffrslwgpya
gwaqavlfsadlrq

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.