PDB entry 1hkx

View 1hkx on RCSB PDB site
Description: crystal structure of calcium/calmodulin-dependent protein kinase
Class: transferase
Keywords: transferase, serine/threonine-protein kinase, calmodulin-binding, phosphorylation, ATP-binding, alternative splicing
Deposited on 2003-03-12, released 2003-06-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.246
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1HKX (Start-3)
    • Uniprot P11798 (4-End)
    Domains in SCOPe 2.06: d1hkxa_
  • Chain 'B':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxb_
  • Chain 'C':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxc_
  • Chain 'D':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxd_
  • Chain 'E':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1HKX (0-3)
    • Uniprot P11798 (4-End)
    Domains in SCOPe 2.06: d1hkxe_
  • Chain 'F':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxf_
  • Chain 'G':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxg_
  • Chain 'H':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1HKX (Start-3)
    • Uniprot P11798 (4-End)
    Domains in SCOPe 2.06: d1hkxh_
  • Chain 'I':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxi_
  • Chain 'J':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxj_
  • Chain 'K':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxk_
  • Chain 'L':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxl_
  • Chain 'M':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxm_
  • Chain 'N':
    Compound: calcium/calmodulin-dependent protein kinase type II alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1hkxn_
  • Heterogens: DTT, CL, TBR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hkxA (A:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxA (A:)
mttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldf
hrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrv
whrrdgkwqivhfhrsgapsv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hkxB (B:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxB (B:)
dedtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyf
enlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrd
gkwqivhfhrsgapsv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1hkxC (C:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxC (C:)
tiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhr
fyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwh
rrdgkwqivhfhrsgapsv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1hkxD (D:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxD (D:)
iededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrf
yfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhr
rdgkwqivhfhrsgapsv

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1hkxE (E:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxE (E:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1hkxF (F:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxF (F:)
tiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhr
fyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwh
rrdgkwqivhfhrsgapsv

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1hkxG (G:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxG (G:)
dedtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyf
enlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrd
gkwqivhfhrsgapsv

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1hkxH (H:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxH (H:)
phmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegl
dfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseet
rvwhrrdgkwqivhfhrsgapsv

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1hkxI (I:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxI (I:)
edtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyfe
nlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrdg
kwqivhfhrsgapsv

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1hkxJ (J:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxJ (J:)
tiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhr
fyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwh
rrdgkwqivhfhrsgapsv

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1hkxK (K:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxK (K:)
edtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyfe
nlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrdg
kwqivhfhrsgapsv

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1hkxL (L:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxL (L:)
edtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyfe
nlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrdg
kwqivhfhrsgapsv

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >1hkxM (M:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxM (M:)
tiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhr
fyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwh
rrdgkwqivhfhrsgapsv

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >1hkxN (N:)
gphmttiededtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlveg
ldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqsee
trvwhrrdgkwqivhfhrsgapsvlph

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkxN (N:)
dedtkvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyf
enlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrd
gkwqivhfhrsgapsv