PDB entry 1hia

View 1hia on RCSB PDB site
Description: kallikrein complexed with hirustasin
Class: complex (protease/inhibitor)
Keywords: complex (protease/inhibitor), tissue kallikrein, serine protease, trypsin, psa, kinin, serpin
Deposited on 1996-12-12, released 1997-12-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.205
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: kallikrein
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1hia.1
  • Chain 'B':
    Compound: kallikrein
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00752 (Start-148)
      • insertion (54)
      • insertion (76)
      • insertion (80)
      • conflict (144)
    Domains in SCOPe 2.07: d1hia.1
  • Chain 'I':
    Compound: hirustasin
    Species: Hirudo medicinalis [TaxId:6421]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1hiai_
  • Chain 'J':
    Compound: hirustasin
    Species: Hirudo medicinalis [TaxId:6421]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1hiaj_
  • Chain 'X':
    Compound: kallikrein
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1hia.2
  • Chain 'Y':
    Compound: kallikrein
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00752 (Start-148)
      • insertion (54)
      • insertion (76)
      • insertion (80)
      • conflict (144)
    Domains in SCOPe 2.07: d1hia.2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1hiaA (A:)
iiggreceknshpwqvaiyhyssfqcggvlvnpkwvltaahckndnyevwlgrhnlfene
ntaqffgvtadfphpgfnls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hiaB (B:)
adgkdyshdlmllrlqspakitdavkvlelptqepelgstceasgwgsiepgpddfefpd
eiqcvqltllqntfcadahpdkvtesmlcagylpggkdtcmgdsggplicngmwqgitsw
ghtpcgsankpsiytklifyldwiddtitenp

    Sequence, based on observed residues (ATOM records): (download) 
    >1hiaB (B:)
gkdyshdlmllrlqspakitdavkvlelptqepelgstceasgwgsiepgpddfefpdei
qcvqltllqntfcadahpdkvtesmlcagylpggkdtcmgdsggplicngmwqgitswgh
tpcgsankpsiytklifyldwiddtitenp

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1hiaI (I:)
tcggetcsaaqvclkgkcvcnevhcrirckyglkkdengceypcscak

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1hiaJ (J:)
tcggetcsaaqvclkgkcvcnevhcrirckyglkkdengceypcscak

  • Chain 'X':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1hiaX (X:)
iiggreceknshpwqvaiyhyssfqcggvlvnpkwvltaahckndnyevwlgrhnlfene
ntaqffgvtadfphpgfnls

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >1hiaY (Y:)
adgkdyshdlmllrlqspakitdavkvlelptqepelgstceasgwgsiepgpddfefpd
eiqcvqltllqntfcadahpdkvtesmlcagylpggkdtcmgdsggplicngmwqgitsw
ghtpcgsankpsiytklifyldwiddtitenp

    Sequence, based on observed residues (ATOM records): (download) 
    >1hiaY (Y:)
gkdyshdlmllrlqspakitdavkvlelptqepelgstceasgwgsiepgpddfefpdei
qcvqltllqntfcadahpdkvtesmlcagylpggkdtcmgdsggplicngmwqgitswgh
tpcgsankpsiytklifyldwiddtitenp