PDB entry 1hd7

View 1hd7 on RCSB PDB site
Description: a second divalent metal ion in the active site of a new crystal form of human apurinic/apyridinimic endonuclease, ape1, and its implications for the catalytic mechanism
Class: DNA repair
Keywords: DNA repair, endonuclease, ape1, hap1, ref-1
Deposited on 2000-11-09, released 2001-02-16
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.205
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-(apurinic or apyrimidinic site) lyase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1HD7
    • Uniprot P27695 (Start-317)
    Domains in SCOPe 2.02: d1hd7a_
  • Heterogens: PB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hd7A (A:)
mpkrgkkgavaedgdelrtepeakksktaakkndkeaagegpalyedppdqktspsgkpa
tlkicswnvdglrawikkkgldwvkeeapdilclqetkcsenklpaelqelpglshqyws
apsdkegysgvgllsrqcplkvsygigdeehdqegrvivaefdsfvlvtayvpnagrglv
rleyrqrwdeafrkflkglasrkplvlcgdlnvaheeidlrnpkgnkknagftpqerqgf
gellqavpladsfrhlypntpyaytfwtymmnarsknvgwrldyfllshsllpalcdski
rskalgsdhcpitlylal

    Sequence, based on observed residues (ATOM records): (download) 
    >1hd7A (A:)
lyedppdqktspsgkpatlkicswnvdglrawikkkgldwvkeeapdilclqetkcsegl
shqywsapysgvgllsrqcplkvsygigdeehdqegrvivaefdsfvlvtayvpnagrgl
vrleyrqrwdeafrkflkglasrkplvlcgdlnvaheeidlrnpkgnkknagftpqerqg
fgellqavpladsfrhlypntpyaytfwtymmnarsknvgwrldyfllshsllpalcdsk
irskalgsdhcpitlylal