PDB entry 1h15

View 1h15 on RCSB PDB site
Description: X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase.
Class: immune system/transferase
Keywords: IMMUNE SYSTEM/TRANSFERASE, COMPLEX (MHC-ANTIGEN), IMMUNE SYSTEM, MHC, HLA, CLASS II, DR2, DRB5, EBV, DNA POLYMERASE, DNA-DIRECTED DNA POLYMERASE, IMMUNE SYSTEM-TRANSFERASE complex
Deposited on 2002-07-02, released 2002-10-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-06-27, with a file datestamp of 2012-06-22.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.256
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1h15a1, d1h15a2
  • Chain 'B':
    Compound: hla class II histocompatibility antigen, dr beta 1 chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1h15b1, d1h15b2
  • Chain 'C':
    Compound: DNA polymerase
    Species: HUMAN HERPESVIRUS 4, synthetic [TaxId:10376]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1h15d1, d1h15d2
  • Chain 'E':
    Compound: hla class II histocompatibility antigen, dr beta 1 chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1h15e1, d1h15e2
  • Chain 'F':
    Compound: DNA polymerase
    Species: HUMAN HERPESVIRUS 4, synthetic [TaxId:10376]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1h15A (A:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    da
    

    Sequence, based on observed residues (ATOM records): (download)
    >1h15A (A:)
    eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
    iavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwl
    rngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefda
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1h15B (B:)
    gdtrprflqqdkyechffngtervrflhrdiynqeedlrfdsdvgeyravtelgrpdaey
    wnsqkdfledrraavdtycrhnygvgesftvqrrvepkvtvypartqtlqhhnllvcsvn
    gfypgsievrwfrnsqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1h15B (B:)
    dtrprflqqdkyechffngtervrflhrdiynqeedlrfdsdvgeyravtelgrpdaeyw
    nsqkdfledrraavdtycrhnygvgesftvqrrvepkvtvypartqtlqhhnllvcsvng
    fypgsievrwfrnsqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsvt
    spltvewra
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1h15D (D:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    da
    

    Sequence, based on observed residues (ATOM records): (download)
    >1h15D (D:)
    eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
    iavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwl
    rngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefda
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1h15E (E:)
    gdtrprflqqdkyechffngtervrflhrdiynqeedlrfdsdvgeyravtelgrpdaey
    wnsqkdfledrraavdtycrhnygvgesftvqrrvepkvtvypartqtlqhhnllvcsvn
    gfypgsievrwfrnsqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1h15E (E:)
    dtrprflqqdkyechffngtervrflhrdiynqeedlrfdsdvgeyravtelgrpdaeyw
    nsqkdfledrraavdtycrhnygvgesftvqrrvepkvtvypartqtlqhhnllvcsvng
    fypgsievrwfrnsqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsvt
    spltvewra
    

  • Chain 'F':
    No sequence available.