Lineage for d1rukh1 (1ruk H:1-113)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2739519Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2739730Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2740567Species Mouse (Mus musculus), cluster 7.1 [TaxId:10090] [88557] (40 PDB entries)
    Uniprot P18532 # HV61_MOUSE Ig heavy chain V region 1B43 precursor
  8. 2740569Domain d1rukh1: 1ruk H:1-113 [97859]
    Other proteins in same PDB: d1rukh2, d1rukl1, d1rukl2
    part of cationic cyclization catalytic Fab 4C6
    complexed with act, bez, gol

Details for d1rukh1

PDB Entry: 1ruk (more details), 1.4 Å

PDB Description: Crystal structure (C) of native cationic cyclization antibody 4C6 fab at pH 4.6 with a data set collected at SSRL beamline 9-1
PDB Compounds: (H:) immunoglobulin igg2a, heavy chain

SCOPe Domain Sequences for d1rukh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1rukh1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 7.1 [TaxId: 10090]}

SCOPe Domain Coordinates for d1rukh1:

Click to download the PDB-style file with coordinates for d1rukh1.
(The format of our PDB-style files is described here.)

Timeline for d1rukh1:

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