SCOP 1.67: Domain d1pr9b_: 1pr9 B:

Lineage for d1pr9b_ (1pr9 B:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (40 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Carbonyl reductase [51765] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102144] (1 PDB entry)
   dicarbonyl/L-xylulose reductase

8. Domain d1pr9b_: 1pr9 B: [95061]
   complexed with 2hp, k, nap

Details for d1pr9b_

PDB Entry: 1pr9, 1.96 Å

PDB Description: human l-xylulose reductase holoenzyme

SCOP Domain Sequences for d1pr9b_:

Sequence; same for both SEQRES and ATOM records:

>d1pr9b_ c.2.1.2 (B:) Carbonyl reductase {Human (Homo sapiens)}
melflagrrvlvtgagkgigrgtvqalhatgarvvavsrtqadldslvrecpgiepvcvd
lgdweateralgsvgpvdllvnnaavallqpflevtkeafdrsfevnlraviqvsqivar
gliargvpgaivnvssqcsqravtnhsvycstkgaldmltkvmalelgphkirvnavnpt
vvmtsmgqatwsdphkaktmlnriplgkfaevehvvnailfllsdrsgmttgstlpvegg
fwac

Timeline for d1pr9b_:

• d1pr9b_ is new in SCOP 1.67
  
• d1pr9b_ appears in SCOP 1.69
  
• d1pr9b_ appears in the current release, SCOPe 2.08