SCOPe 2.07: Domain d1np3b1: 1np3 B:183-327

Lineage for d1np3b1 (1np3 B:183-327)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
   multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry

4. Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (13 families)
   N-terminal domain is Rossmann-fold with a family-specific C-terminal extension

5. Family a.100.1.2: Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI) [48184] (3 proteins)

6. Protein Class I ketol-acid reductoisomerase [89101] (1 species)

7. Species Pseudomonas aeruginosa [TaxId:287] [89102] (1 PDB entry)

8. Domain d1np3b1: 1np3 B:183-327 [85948]
   Other proteins in same PDB: d1np3a2, d1np3b2, d1np3c2, d1np3d2

Details for d1np3b1

PDB Entry: 1np3, 2 Å

PDB Description: Crystal structure of class I acetohydroxy acid isomeroreductase from Pseudomonas aeruginosa

PDB Compounds: (B:) Ketol-acid reductoisomerase

SCOPe Domain Sequences for d1np3b1:

Sequence; same for both SEQRES and ATOM records:

>d1np3b1 a.100.1.2 (B:183-327) Class I ketol-acid reductoisomerase {Pseudomonas aeruginosa [TaxId: 287]}
fkdetetdlfgeqavlcggcvelvkagfetlveagyapemayfeclhelklivdlmyegg
ianmnysisnnaeygeyvtgpevinaesraamrnalkriqdgeyakmfitegaanypsmt
ayrrnnaahpieqigeklrammpwi

Timeline for d1np3b1:

• d1np3b1 first appeared in SCOP 1.65
  
• d1np3b1 appears in SCOPe 2.06
  
• d1np3b1 appears in the current release, SCOPe 2.08