Lineage for d1mhpa_ (1mhp A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2892194Fold c.62: vWA-like [53299] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
  4. 2892195Superfamily c.62.1: vWA-like [53300] (6 families) (S)
  5. 2892196Family c.62.1.1: Integrin A (or I) domain [53301] (12 proteins)
  6. 2892236Protein Integrin alpha1-beta1 [53310] (2 species)
  7. 2892245Species Norway rat (Rattus norvegicus) [TaxId:10116] [53312] (3 PDB entries)
  8. 2892250Domain d1mhpa_: 1mhp A: [84965]
    Other proteins in same PDB: d1mhph1, d1mhph2, d1mhpl1, d1mhpl2, d1mhpx_, d1mhpy_
    complexed with humanized neutralizing Fab
    complexed with mn

Details for d1mhpa_

PDB Entry: 1mhp (more details), 2.8 Å

PDB Description: crystal structure of a chimeric alpha1 integrin i-domain in complex with the fab fragment of a humanized neutralizing antibody
PDB Compounds: (A:) integrin alpha 1, (RESIDUES 169-360)

SCOPe Domain Sequences for d1mhpa_:

Sequence, based on SEQRES records: (download)

>d1mhpa_ c.62.1.1 (A:) Integrin alpha1-beta1 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
tqldivivldgsnsiypwesviaflndllkrmdigpkqtqvgivqygenvthefnlnkys
steevlvaankivqrggrqtmtalgidtarkeafteargarrgvkkvmvivtdgeshdny
rlkqviqdcedeniqrfsiailghynrgnlstekfveeiksiaseptekhffnvsdelal
vtivkalgerif

Sequence, based on observed residues (ATOM records): (download)

>d1mhpa_ c.62.1.1 (A:) Integrin alpha1-beta1 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
tqldivivldgsnsiypwesviaflndllkrmdigpkqtqvgivqygenvthefnlnkys
steevlvaankivqrggrqtmtalgidtarkeafteargarrgvkkvmvivtdgeshdny
rlkqviqdcedeniqrfsiailgtekfveeiksiaseptekhffnvsdelalvtivkalg
erif

SCOPe Domain Coordinates for d1mhpa_:

Click to download the PDB-style file with coordinates for d1mhpa_.
(The format of our PDB-style files is described here.)

Timeline for d1mhpa_: