SCOPe 2.08: Protein: Transcription corepressor CtbP

Lineage for Protein: Transcription corepressor CtbP

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)
Family c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain [51830] (10 proteins)
this domain interrupts the other domain which defines family
Protein Transcription corepressor CtbP [82298] (2 species)
C-terminal binding protein 1; a dehydrogenase

Species:

Human (Homo sapiens), Ctbp1 [TaxId:9606] [82299] (4 PDB entries)
1. Domain for 1mx3:
  - Domain d1mx3a1: 1mx3 A:126-318 [79638]
    Other proteins in same PDB: d1mx3a2, d1mx3a3
    complexed with acy, nad
2. Domain for 4lce:
  - Domain d4lcea2: 4lce A:126-318 [237834]
    Other proteins in same PDB: d4lcea1, d4lcea3
    automated match to d1mx3a1
    complexed with kmt, nad
3. Domain for 4u6q:
  - Domain d4u6qa2: 4u6q A:126-318 [271982]
    Other proteins in same PDB: d4u6qa1, d4u6qa3
    automated match to d1mx3a1
    complexed with 3cr, ca, fmt, nai
4. Domain for 4u6s:
  - Domain d4u6sa2: 4u6s A:126-318 [271976]
    Other proteins in same PDB: d4u6sa1, d4u6sa3
    automated match to d1mx3a1
    complexed with ca, fmt, nad, ppy
Norway rat (Rattus norvegicus), Ctbp3 [TaxId:10116] [89529] (2 PDB entries)
1. Domain for 1hku:
  - Domain d1hkua1: 1hku A:115-307 [83557]
    Other proteins in same PDB: d1hkua2
    complexed with fmt, gol, nad
2. Domain for 1hl3:
  - Domain d1hl3a1: 1hl3 A:115-307 [83585]
    Other proteins in same PDB: d1hl3a2
    complexed with nad

More info for Protein Transcription corepressor CtbP from c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain

Timeline for Protein Transcription corepressor CtbP from c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain:

Protein Transcription corepressor CtbP from c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain first appeared in SCOP 1.63
Protein Transcription corepressor CtbP from c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain appears in SCOPe 2.07