SCOPe 2.03: Domain d1lv2a_: 1lv2 A:

Lineage for d1lv2a_ (1lv2 A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Hepatocyte nuclear factor 4-gamma [81918] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [81919] (1 PDB entry)

8. Domain d1lv2a_: 1lv2 A: [78230]
   complexed with plm

Details for d1lv2a_

PDB Entry: 1lv2, 2.7 Å

PDB Description: hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

PDB Compounds: (A:) Hepatocyte nuclear factor 4-gamma

SCOPe Domain Sequences for d1lv2a_:

Sequence, based on SEQRES records:

>d1lv2a_ a.123.1.1 (A:) Hepatocyte nuclear factor 4-gamma {Human (Homo sapiens) [TaxId: 9606]}
aagsintlaqaevrsrqisvsspgsstdinvkkiasigdvcesmkqqllvlvewakyipa
fcelplddqvallrahagehlllgatkrsmmykdilllgnnyvihrnsceveisrvanrv
ldelvrpfqeiqiddneyaclkaivffdpdakglsdpvkiknmrfqvqigledyindrqy
dsrgrfgelllllptlqsitwqmieqiqfvklfgmvkidnllqemllgg

Sequence, based on observed residues (ATOM records):

>d1lv2a_ a.123.1.1 (A:) Hepatocyte nuclear factor 4-gamma {Human (Homo sapiens) [TaxId: 9606]}
aagsintlaqaevrsrqisvsstdinvkkiasigdvcesmkqqllvlvewakyipafcel
plddqvallrahagehlllgatkrsmmykdilllgnnyvihrnsceveisrvanrvldel
vrpfqeiqiddneyaclkaivffdpdakglsdpvkiknmrfqvqigledyindrqydsrg
rfgelllllptlqsitwqmieqiqfvklfgmvkidnllqemllgg

Timeline for d1lv2a_:

• d1lv2a_ first appeared in SCOP 1.63
  
• d1lv2a_ appears in SCOPe 2.02
  
• d1lv2a_ appears in SCOPe 2.04
  
• d1lv2a_ appears in the current release, SCOPe 2.08, called d1lv2a1